C3 and C4 complement levels in AQP4-IgG-positive NMOSD and in MOGAD
F Pache, M Ringelstein, O Aktas, I Kleiter… - Journal of …, 2021 - Elsevier
While complement-dependent cytotoxicity (CDC) is a known effector mechanism in
aquaporin-4-immunoglobulin (Ig) G-positive (AQP4-IgG+) neuromyelitis optica spectrum …
aquaporin-4-immunoglobulin (Ig) G-positive (AQP4-IgG+) neuromyelitis optica spectrum …
More Efficient Complement Activation by Anti–Aquaporin-4 Compared With Anti–Myelin Oligodendrocyte Glycoprotein Antibodies
M Lerch, K Schanda, E Lafon, R Würzner… - Neurology …, 2022 - AAN Enterprises
Background and Objectives The objective was to study complement-mediated cytotoxicity
induced by immunoglobulin G (IgG) anti–aquaporin-4 antibodies (AQP4-IgG) and anti …
induced by immunoglobulin G (IgG) anti–aquaporin-4 antibodies (AQP4-IgG) and anti …
[HTML][HTML] Plasma complement 3 and complement 4 are promising biomarkers for distinguishing NMOSD from MOGAD and are associated with the blood-brain-barrier …
L Lin, Y Wu, H Hang, J Lu, Y Ding - Frontiers in Immunology, 2022 - frontiersin.org
Background and Objective Neuromyelitis optica spectrum disorders (NMOSD) and myelin
oligodendrocyte glycoprotein antibody (MOG-IgG) associated disease (MOGAD) are …
oligodendrocyte glycoprotein antibody (MOG-IgG) associated disease (MOGAD) are …
The clinical value of complement proteins in differentiating AQP4-IgG-positive from MOG-IgG-positive neuromyelitis optica spectrum disorders
C Qin, B Chen, R Tao, M Chen, X Ma, K Shang… - Multiple Sclerosis and …, 2019 - Elsevier
Background Neuromyelitis optica spectrum disorder (NMOSD) refers to a range of
autoimmune inflammatory demyelinating diseases affecting the optic nerves, spinal cord …
autoimmune inflammatory demyelinating diseases affecting the optic nerves, spinal cord …
[HTML][HTML] Cytoprotective IgG antibodies in sera from a subset of patients with AQP4-IgG seropositive neuromyelitis optica spectrum disorder
L Tradtrantip, MR Yeaman, AS Verkman - Scientific Reports, 2021 - nature.com
Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune inflammatory disease of
the central nervous system. Most NMOSD patients are seropositive for immunoglobulin G …
the central nervous system. Most NMOSD patients are seropositive for immunoglobulin G …
Myelin oligodendrocyte glycoprotein-IgG contributes to oligodendrocytopathy in the presence of complement, distinct from astrocytopathy induced by AQP4-IgG
L Fang, X Kang, Z Wang, S Wang, J Wang, Y Zhou… - Neuroscience …, 2019 - Springer
Immunoglobulin G against myelin oligodendrocyte glycoprotein (MOG-IgG) is detectable in
neuromyelitis optica spectrum disorder (NMOSD) without aquaporin-4 IgG (AQP4-IgG), but …
neuromyelitis optica spectrum disorder (NMOSD) without aquaporin-4 IgG (AQP4-IgG), but …
[HTML][HTML] Complement activating antibodies to myelin oligodendrocyte glycoprotein in neuromyelitis optica and related disorders
S Mader, V Gredler, K Schanda, K Rostasy… - Journal of …, 2011 - Springer
Background Serum autoantibodies against the water channel aquaporin-4 (AQP4) are
important diagnostic biomarkers and pathogenic factors for neuromyelitis optica (NMO) …
important diagnostic biomarkers and pathogenic factors for neuromyelitis optica (NMO) …
Difference in the source of anti-AQP4-IgG and anti-MOG-IgG antibodies in CSF in patients with neuromyelitis optica spectrum disorder
T Akaishi, T Takahashi, T Misu, K Kaneko, Y Takai… - Neurology, 2021 - AAN Enterprises
Objective To elucidate the differences in the source and in the level of intrathecal synthesis
between anti–aquaporin-4 antibodies (AQP4-IgG) and anti-myelin oligodendrocyte …
between anti–aquaporin-4 antibodies (AQP4-IgG) and anti-myelin oligodendrocyte …
Clinical utility of AQP4-IgG titers and measures of complement-mediated cell killing in NMOSD
J Jitprapaikulsan, JP Fryer, M Majed… - Neurology …, 2020 - AAN Enterprises
Objective To investigate whether aquaporin-4–immunoglobulin G (AQP4-IgG) titers and
measures of complement-mediated cell killing are clinically useful to predict the occurrence …
measures of complement-mediated cell killing are clinically useful to predict the occurrence …
CSF cytokine profile in MOG-IgG+ neurological disease is similar to AQP4-IgG+ NMOSD but distinct from MS: a cross-sectional study and potential therapeutic …
K Kaneko, DK Sato, I Nakashima, R Ogawa… - Journal of Neurology …, 2018 - jnnp.bmj.com
Objective To evaluate cerebrospinal fluid (CSF) cytokine profiles in myelin oligodendrocyte
glycoprotein IgG-positive (MOG-IgG+) disease in adult and paediatric patients. Methods In …
glycoprotein IgG-positive (MOG-IgG+) disease in adult and paediatric patients. Methods In …
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