Background: Cerebrovascular health plays an important role in cognitive health in older
adults. Cerebrovascular reactivity (CVR), a measure of cerebrovascular health, changes in …

INTRODUCTION Vascular contributions to cognitive impairment and dementia (VCID)
represent a major factor in cognitive decline in older adults. The present study examined the …

Objective To determine whether MRI-based cerebrovascular reactivity (CVR) can predict
cognitive performance independently of Alzheimer pathologic markers, we studied the …

Background: Older adults with mild cognitive impairment (MCI) exhibit deficits in
cerebrovascular reactivity (CVR), suggesting CVR is a biomarker for vascular contributions …

Although cerebrovascular factors are the second leading cause of cognitive impairment and
dementia in elderly, the precise spatial and temporal trajectories of vascular decline in aging …

Background: Recent investigations now suggest that cerebrovascular reactivity (CVR) is
impaired in Alzheimer's disease (AD) and may underpin part of the disease's neurovascular …

Vascular risk factors (eg, obesity and hypertension) are associated with cerebral small
vessel disease, Alzheimer's disease (AD) pathology, and dementia. Reduced perfusion may …

Research suggests an association between cerebrovascular health and cognitive decline,
but previous work is limited by its cross-sectional nature or short (< 1–2 years) follow-up. Our …

Background: Increasing evidence indicates that cerebrovascular dysfunction may precede
cognitive decline in aging and Alzheimer's disease (AD). Reduced cerebral blood flow …

Vascular pathology is the second leading cause of cognitive impairment and represents a
major contributing factor in mixed dementia. However, biomarkers for vascular cognitive …