To better understand host-virus genetic dependencies and find potential therapeutic targets
for COVID-19, we performed a genome-scale CRISPR loss-of-function screen to identify …

The Coronaviridae are a family of viruses that cause disease in humans ranging from mild
respiratory infection to potentially lethal acute respiratory distress syndrome. Finding host …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a range of
symptoms in infected individuals, from mild respiratory illness to acute respiratory distress …

The global spread of SARS-CoV-2 led to major economic and health challenges worldwide.
Revealing host genes essential for infection by multiple variants of SARS-CoV-2 can provide …

CRISPR knockout (KO) screens have identified host factors regulating severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) replication. Here, we conducted a meta …

Summary The coronavirus disease 2019 (COVID-19) pandemic has claimed the lives of
over one million people worldwide. The causative agent, severe acute respiratory syndrome …

Complementary genome-wide CRISPR-Cas9 screens performed by multiple groups reveal
new insights into SARS-CoV-2 biology including aspects of viral entry, translation …

The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has
devastated the global economy and claimed more than 1.7 million lives, presenting an …

Identification of host genes essential for severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection may reveal novel therapeutic targets and inform our understanding …

Abstract The SARS-CoV-2 coronavirus, the etiologic agent responsible for COVID-19
coronavirus disease, is a global threat. To better understand viral tropism, we assessed the …