[HTML][HTML] Identification of required host factors for SARS-CoV-2 infection in human cells
To better understand host-virus genetic dependencies and find potential therapeutic targets
for COVID-19, we performed a genome-scale CRISPR loss-of-function screen to identify …
for COVID-19, we performed a genome-scale CRISPR loss-of-function screen to identify …
Genetic screens identify host factors for SARS-CoV-2 and common cold coronaviruses
The Coronaviridae are a family of viruses that cause disease in humans ranging from mild
respiratory infection to potentially lethal acute respiratory distress syndrome. Finding host …
respiratory infection to potentially lethal acute respiratory distress syndrome. Finding host …
Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection
SB Biering, SA Sarnik, E Wang, JR Zengel, SR Leist… - Nature …, 2022 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a range of
symptoms in infected individuals, from mild respiratory illness to acute respiratory distress …
symptoms in infected individuals, from mild respiratory illness to acute respiratory distress …
Genome-wide CRISPR screens identify GATA6 as a proviral host factor for SARS-CoV-2 via modulation of ACE2
M Israeli, Y Finkel, Y Yahalom-Ronen, N Paran… - Nature …, 2022 - nature.com
The global spread of SARS-CoV-2 led to major economic and health challenges worldwide.
Revealing host genes essential for infection by multiple variants of SARS-CoV-2 can provide …
Revealing host genes essential for infection by multiple variants of SARS-CoV-2 can provide …
Bidirectional genome-wide CRISPR screens reveal host factors regulating SARS-CoV-2, MERS-CoV and seasonal HCoVs
A Rebendenne, P Roy, B Bonaventure… - Nature …, 2022 - nature.com
CRISPR knockout (KO) screens have identified host factors regulating severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) replication. Here, we conducted a meta …
respiratory syndrome coronavirus 2 (SARS-CoV-2) replication. Here, we conducted a meta …
Genome-scale identification of SARS-CoV-2 and pan-coronavirus host factor networks
WM Schneider, JM Luna, HH Hoffmann… - Cell, 2021 - cell.com
Summary The coronavirus disease 2019 (COVID-19) pandemic has claimed the lives of
over one million people worldwide. The causative agent, severe acute respiratory syndrome …
over one million people worldwide. The causative agent, severe acute respiratory syndrome …
[HTML][HTML] A Crisp (r) new perspective on SARS-CoV-2 biology
AL Bailey, MS Diamond - Cell, 2021 - cell.com
Complementary genome-wide CRISPR-Cas9 screens performed by multiple groups reveal
new insights into SARS-CoV-2 biology including aspects of viral entry, translation …
new insights into SARS-CoV-2 biology including aspects of viral entry, translation …
Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors
HH Hoffmann, FJ Sánchez-Rivera, WM Schneider… - Cell host & …, 2021 - cell.com
The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has
devastated the global economy and claimed more than 1.7 million lives, presenting an …
devastated the global economy and claimed more than 1.7 million lives, presenting an …
Genome-wide CRISPR screens reveal host factors critical for SARS-CoV-2 infection
Identification of host genes essential for severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection may reveal novel therapeutic targets and inform our understanding …
(SARS-CoV-2) infection may reveal novel therapeutic targets and inform our understanding …
[HTML][HTML] SARS-CoV-2 entry genes are most highly expressed in nasal goblet and ciliated cells within human airways
Abstract The SARS-CoV-2 coronavirus, the etiologic agent responsible for COVID-19
coronavirus disease, is a global threat. To better understand viral tropism, we assessed the …
coronavirus disease, is a global threat. To better understand viral tropism, we assessed the …
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