Propionibacterium acnes and Acne Vulgaris: New Insights from the Integration of Population Genetic, Multi-Omic, Biochemical and Host-Microbe Studies

J McLaughlin, S Watterson, AM Layton, AJ Bjourson… - Microorganisms, 2019 - mdpi.com
The anaerobic bacterium Propionibacterium acnes is believed to play an important role in
the pathophysiology of the common skin disease acne vulgaris. Over the last 10 years our …

Comparative Genomics and Transcriptomics of Propionibacterium acnes

E Brzuszkiewicz, J Weiner, A Wollherr, A Thürmer… - PLoS …, 2011 - journals.plos.org
The anaerobic Gram-positive bacterium Propionibacterium acnes is a human skin
commensal that is occasionally associated with inflammatory diseases. Recent work has …

Population Genetic Analysis of Propionibacterium acnes Identifies a Subpopulation and Epidemic Clones Associated with Acne

HB Lomholt, M Kilian - PloS one, 2010 - journals.plos.org
The involvement of Propionibacterium acnes in the pathogenesis of acne is controversial,
mainly owing to its dominance as an inhabitant of healthy skin. This study tested the …

[HTML][HTML] Different Propionibacterium acnes phylotypes induce distinct immune responses and express unique surface and secreted proteomes

Y Yu, J Champer, GW Agak, S Kao, RL Modlin… - Journal of Investigative …, 2016 - Elsevier
Propionibacterium acnes is a skin commensal bacterium that contributes to the development
of acne vulgaris and other infections. Recent work revealed that P. acnes clinical isolates …

An Expanded Multilocus Sequence Typing Scheme for Propionibacterium acnes: Investigation of 'Pathogenic', 'Commensal' and Antibiotic Resistant Strains

A McDowell, E Barnard, I Nagy, A Gao, S Tomida, H Li… - 2012 - journals.plos.org
The Gram-positive bacterium Propionibacterium acnes is a member of the normal human
skin microbiota and is associated with various infections and clinical conditions. There is …

Proteomic identification of secreted proteins of Propionibacterium acnes

C Holland, TN Mak, U Zimny-Arndt, M Schmid… - BMC microbiology, 2010 - Springer
Abstract Background The anaerobic Gram-positive bacterium Propionibacterium acnes is a
human skin commensal that resides preferentially within sebaceous follicles; however, it …

Propionibacterium acnes: an update on its role in the pathogenesis of acne

C Beylot, N Auffret, F Poli, JP Claudel… - Journal of the …, 2014 - Wiley Online Library
In recent years, significant progress has been made in the understanding of the
pathophysiological mechanisms of acne and the role of Propionibacterium acnes. With this …

A novel multilocus sequence typing scheme for the opportunistic pathogen Propionibacterium acnes and characterization of type I cell surface-associated antigens

A McDowell, A Gao, E Barnard, C Fink… - …, 2011 - microbiologyresearch.org
We have developed a novel multilocus sequence typing (MLST) scheme and database
(http://pubmlst. org/pacnes/) for Propionibacterium acnes based on the analysis of seven …

Pan-genome and comparative genome analyses of propionibacterium acnes reveal its genomic diversity in the healthy and diseased human skin microbiome

S Tomida, L Nguyen, BH Chiu, J Liu, E Sodergren… - mbio, 2013 - Am Soc Microbiol
Propionibacterium acnes constitutes a major part of the skin microbiome and contributes to
human health. However, it has also been implicated as a pathogenic factor in several …

[HTML][HTML] Propionibacterium acnes strain populations in the human skin microbiome associated with acne

S Fitz-Gibbon, S Tomida, BH Chiu, L Nguyen… - Journal of investigative …, 2013 - Elsevier
The human skin microbiome has important roles in skin health and disease. However,
bacterial population structure and diversity at the strain level is poorly understood. We …