Primary biliary cholangitis

A Lleo, GQ Wang, ME Gershwin, GM Hirschfield - The Lancet, 2020 - thelancet.com
Primary biliary cholangitis is an autoimmune liver disease that predominantly affects women.
It is characterised by a chronic and destructive, small bile duct, granulomatous lymphocytic …

Current and potential treatments for primary biliary cholangitis

RA Shah, KV Kowdley - The Lancet Gastroenterology & Hepatology, 2020 - thelancet.com
Up to 40% of patients with primary biliary cholangitis have an incomplete response to first-
line treatment with ursodeoxycholic acid. Obeticholic acid was approved by the US Food …

[HTML][HTML] Primary biliary cholangitis: Epidemiology, prognosis, and treatment

J Trivella, BV John, C Levy - Hepatology communications, 2023 - journals.lww.com
Primary biliary cholangitis (PBC) is a chronic cholestatic autoimmune liver disease
characterized by a destructive, small duct, and lymphocytic cholangitis, and marked by the …

The British Society of Gastroenterology/UK-PBC primary biliary cholangitis treatment and management guidelines

GM Hirschfield, JK Dyson, GJM Alexander… - Gut, 2018 - gut.bmj.com
Primary biliary cholangitis (formerly known as primary biliary cirrhosis, PBC) is an
autoimmune liver disease in which a cycle of immune mediated biliary epithelial cell injury …

Primary biliary cirrhosis

EJ Carey, AH Ali, KD Lindor - The Lancet, 2015 - thelancet.com
Primary biliary cirrhosis is a chronic cholestatic liver disease characterised by destruction of
small intrahepatic bile ducts, leading to fibrosis and potential cirrhosis through resulting …

EASL Clinical Practice Guidelines: The diagnosis and management of patients with primary biliary cholangitis

GM Hirschfield, U Beuers, C Corpechot, P Invernizzi… - Journal of …, 2017 - Elsevier
Primary biliary cholangitis (PBC) is a chronic inflammatory autoimmune cholestatic liver
disease, which when untreated will culminate in end-stage biliary cirrhosis. Diagnosis is …

Primary biliary cholangitis: pathogenesis and therapeutic opportunities

AF Gulamhusein, GM Hirschfield - Nature Reviews Gastroenterology & …, 2020 - nature.com
Primary biliary cholangitis is a chronic, seropositive and female-predominant inflammatory
and cholestatic liver disease, which has a variable rate of progression towards biliary …

Primary biliary cirrhosis

JA Talwalkar, KD Lindor - The Lancet, 2003 - thelancet.com
Primary biliary cirrhosis is a chronic cholestatic liver disease of adults. This disorder is
characterised histologically by chronic non-suppurative destruction of interlobular bile ducts …

[HTML][HTML] A practical review of primary biliary cholangitis for the gastroenterologist

FQ Onofrio, GM Hirschfield… - Gastroenterology & …, 2019 - ncbi.nlm.nih.gov
Primary biliary cholangitis (PBC) is an autoimmune chronic cholestatic liver disease
characterized by biliary destruction and progressive intrahepatic cholestasis. PBC primarily …

Primary biliary cholangitis: a comprehensive overview

A Lleo, S Marzorati, JM Anaya, ME Gershwin - Hepatology international, 2017 - Springer
Primary biliary cholangitis (PBC) is an autoimmune liver disease characterized by biliary
destruction, progressive cholestasis, and potentially liver cirrhosis. Patients develop a well …