Objective To study serious harms associated with selective serotonin and serotonin-
norepinephrine reuptake inhibitors. Design Systematic review and meta-analysis. Main …

Objective To quantify the risk of suicidality and violence when selective serotonin and
serotonin-norepinephrine reuptake inhibitors are given to adult healthy volunteers with no …

Objective To examine the risk of suicidal behaviour within clinical trials of antidepressants in
adults. Design Meta-analysis of 372 double blind randomised placebo controlled trials …

Hammad and colleagues 2 first reported, in a meta-analysis of 24 randomized clinical trials
(RCTs)(20 of which had data on suicidal events), that antidepressant use was associated …

Objective To assess the associations between different antidepressant treatments and the
rates of suicide and attempted suicide or self harm in people with depression. Design Cohort …

Objective To investigate whether selective serotonin reuptake inhibitor (SSRI)
antidepressants are associated with an increased risk of suicide related outcomes in adults …

Objective To compare the risk of non-fatal self harm and suicide in patients taking selective
serotonin reuptake inhibitors (SSRIs) with that of patients taking tricyclic antidepressants, as …

In the past few years several papers have reported critically on the risk of suicidal thoughts
and behaviour associated with antidepressants, primarily SSRIs. The risk-benefit ratio of …

The last years have witnessed a controversy about antidepressant use that is still in the
balance. On one side, treating depression with antidepressants seems to reduce the risk of …

Background: Studies of the adverse effects of antidepressants tend to focus on biological
symptoms. The prevalence of suicidality and withdrawal effects are currently a source of …