[HTML][HTML] Genome-wide loss of heterozygosity predicts aggressive, treatment-refractory behavior in pituitary neuroendocrine tumors
AL Lin, VA Rudneva, AL Richards, Y Zhang… - Acta …, 2024 - Springer
Pituitary neuroendocrine tumors (PitNETs) exhibiting aggressive, treatment-refractory
behavior are the rare subset that progress after surgery, conventional medical therapies …
behavior are the rare subset that progress after surgery, conventional medical therapies …
Pituitary tumors: genetic and molecular factors underlying pathogenesis and clinical behavior
A Spada, G Mantovani, AG Lania, D Treppiedi… - …, 2022 - karger.com
Pituitary neuroendocrine tumors (PitNETs) are the most common intracranial neoplasms.
Although generally benign, they can show a clinically aggressive course, with local invasion …
Although generally benign, they can show a clinically aggressive course, with local invasion …
Genomics and epigenomics of pituitary tumors: what do pathologists need to know?
Molecular pathology has advanced our understanding of many tumors and offers
opportunities to identify novel therapies. In the pituitary, the field has uncovered several …
opportunities to identify novel therapies. In the pituitary, the field has uncovered several …
Clinical identification of oncogenic drivers and copy-number alterations in pituitary tumors
Pituitary tumors are the second most common adult primary brain tumor, with a variable
clinical course. Recent work has identified a number of genetic determinants of pituitary …
clinical course. Recent work has identified a number of genetic determinants of pituitary …
Epigenomic and somatic mutation profile of pituitary adenomas (PAs)/pituitary neuroendocrine tumors (PitNETs)
F Guaraldi, L Morandi, M Zoli, A Righi… - Endocrine …, 2022 - endocrine-abstracts.org
Background: Pituitary adenomas (PAs)/Pituitary Neuroendocrine Tumors (PitNETs) are a
complex and heterogeneous group of lesions. Genetic and epigenetic studies have been …
complex and heterogeneous group of lesions. Genetic and epigenetic studies have been …
[HTML][HTML] Transcriptomic profiles of normal pituitary cells and pituitary neuroendocrine tumor cells
Simple Summary The molecular pathogenesis of pituitary neuroendocrine tumors (PitNETs)
involves the interplay of many genes and transcription factors in the setting of a diverse …
involves the interplay of many genes and transcription factors in the setting of a diverse …
SAT603 A Heterogeneous Genetic Background Underlies Familial And Young-onset Pituitary Tumors
JM Zuarth-Vazquez, RG Rebollar-Vega… - Journal of the …, 2023 - academic.oup.com
Abstract Disclosure: JM Zuarth-Vazquez: None. RG Rebollar-Vega: None. C. Ramírez-
Rentería: None. WE Hernández-Núñez: None. M. Torres-Morán: None. AL Franco-Álvarez …
Rentería: None. WE Hernández-Núñez: None. M. Torres-Morán: None. AL Franco-Álvarez …
[HTML][HTML] Whole exome sequencing reveals novel risk genes of pituitary neuroendocrine tumors
R Peculis, V Rovite, K Megnis, I Balcere, A Breiksa… - Plos one, 2022 - journals.plos.org
Somatic genetic alterations in pituitary neuroendocrine tumors (PitNET) tissues have been
identified in several studies, but detection of overlapping somatic PitNET candidate genes is …
identified in several studies, but detection of overlapping somatic PitNET candidate genes is …
[HTML][HTML] Chromosomal instability in the prediction of pituitary neuroendocrine tumors prognosis
H Lasolle, MH Elsensohn, A Wierinckx, E Alix… - Acta neuropathologica …, 2020 - Springer
The purpose of this study was to analyze the impact of copy number variations (CNV) on
sporadic pituitary neuroendocrine tumors (PitNETs) prognosis, to identify specific prognosis …
sporadic pituitary neuroendocrine tumors (PitNETs) prognosis, to identify specific prognosis …
Landscape of genomic alterations in pituitary adenomas
Purpose: Pituitary adenomas are the second most common primary brain tumor, yet their
genetic profiles are incompletely understood. Experimental Design: We performed whole …
genetic profiles are incompletely understood. Experimental Design: We performed whole …