Several methods have been developed for using 31P‐MRS to calculate rates of oxidative
ATP synthesis (ATPOX) during muscular contractions based on assumptions that (1) the …

Key points The oxygen cost of high‐intensity exercise at power outputs above an individual's
lactate threshold (LT) is greater than would be predicted by the linear oxygen consumption …

Key points During maximal exercise, skeletal muscle metabolism and oxygen consumption
remain elevated despite precipitous declines in power. Presently, it is unclear whether these …

Data from 31P-nuclear magnetic resonance spectroscopy of human forearm flexor muscle
were analyzed based on a previously developed model of mitochondrial oxidative …

Energy for muscle contractions is supplied by ATP generated from 1) the net hydrolysis of
phosphocreatine (PCr) through the creatine kinase reaction, 2) oxidative phosphorylation …

Inversion transfer (IT) is a well‐established technique with multiple attractive features for
analysis of kinetics. However, its application in measurement of ATP synthesis rate in vivo …

Key points Heavy‐intensity exercise causes a progressive increase in energy demand that
contributes to exercise limitation. This inefficiency arises within the locomotor muscles and is …

Mitochondrial ATP production is vital for meeting cellular energy demand at rest and during
periods of high ATP turnover. We hypothesized that high-intensity interval training (HIT) …

Net forward adenosine triphosphate (ATP) production rates were calculated from 31P
nuclear magnetic resonance spectroscopy (MRS) kinetic data collected with 1–8 s time …

We measured significant undershoots of the concentrations of free ADP ([ADP]) and Pi ([Pi])
and the free energy of ATP hydrolysis (Δ G ATP) below initial resting levels during recovery …