Extracellular matrix (ECM) plays a central and dynamic role in the creation of tumor
microenvironment. Herein we discuss the emerging biophysical and biochemical aspects of …

Tumor extracellular matrix (ECM) operates in a coordinated mode with cancer and stroma
cells to evoke the multistep process of metastatic potential. The remodeled tumor-associated …

The local microenvironment, or niche, of a cancer cell plays important roles in cancer
development. A major component of the niche is the extracellular matrix (ECM), a complex …

The extracellular matrix (ECM) is a ubiquitous member of the body and is key to the
maintenance of tissue and organ integrity. Initially thought to be a bystander in many cellular …

The tumor microenvironment (TME) is composed of various cell types embedded in an
altered extracellular matrix (ECM). ECM not only serves as a support for tumor cell but also …

Tissues are dynamically shaped by bidirectional communication between resident cells and
the extracellular matrix (ECM) through cell-matrix interactions and ECM remodelling …

The extracellular matrix (ECM) is essential for cell support during homeostasis and plays a
critical role in cancer. Although research often concentrates on the tumor's cellular aspect …

As our understanding of cancer cell biology progresses, it has become clear that tumors are
a heterogenous mixture of different cell populations, some of which contain so called …

The main cause of cancer-related mortality, metastasis, is a complex, multi-step process.
The extracellular matrix (ECM) component of solid tumors has been implicated in metastatic …

Solid tumors are complex organ-like structures that consist not only of tumor cells but also of
vasculature, extracellular matrix (ECM), stromal, and immune cells. Often, this tumor …