Background: It is hypothesized that low selenium concentrations are associated with an
increased risk of cardiovascular disease and that selenium supplements prevent coronary …

Current evidence is insufficient to support a protective role for selenium in cardiovascular
prevention. Large high-quality randomized controlled trials and observational studies are …

Results: Our meta-analysis of prospective studies showed a nonlinear relationship of CVD
risk with blood selenium concentrations across a range of 30–165 μg/l and a significant …

Despite the documented antioxidant and chemopreventive properties of selenium, studies of
selenium intake and supplementation and cardiovascular disease have yielded inconsistent …

Background: Both experimental and observational studies have provided conflicting
evidence on the associations of selenium with incidence and mortality of cardiovascular …

Selenium is an essential trace element that is an integral part of many proteins, with catalytic
and structural functions. The antioxidant properties of some selenoproteins, such as …

Use of selenium enriched foods, supplements and fertilizers has increased markedly in
recent years in the US and other Western countries because of the perception that the anti …

Background Antioxidants have been promoted for cardiovascular disease (CVD) risk
reduction and for the prevention of cancer. Our preliminary analysis suggested that only …

OBJECTIVE: High selenium status has been associated with adverse cardiometabolic
outcomes in selenium-replete populations such as the US. In populations with lower …

Background Selenium is a crucial mineral with antioxidant and immune functions, and
selenium deficiency may increase the risk of coronary heart disease (CHD). However, the …