Odontogenic infection by Porphyromonas gingivalis exacerbates fibrosis in NASH via hepatic stellate cell activation
A Nagasaki, S Sakamoto, C Chea, E Ishida… - Scientific reports, 2020 - nature.com
Odontogenic infection of Porphyromonas gingivalis (Pg.), a major periodontal pathogen,
exacerbates pathological progression of non-alcoholic steatohepatitis (NASH). In this study …
exacerbates pathological progression of non-alcoholic steatohepatitis (NASH). In this study …
Elimination of Porphyromonas gingivalis inhibits liver fibrosis and inflammation in NASH
A Nagasaki, S Sakamoto, T Arai, M Kato… - Journal of Clinical …, 2021 - Wiley Online Library
Aim Non‐alcoholic steatohepatitis (NASH) is a critical liver disease showing potential
progression to liver cirrhosis/cancer. Previously, we had reported that odontogenic infection …
progression to liver cirrhosis/cancer. Previously, we had reported that odontogenic infection …
Dental infection of Porphyromonas gingivalis exacerbates high fat diet-induced steatohepatitis in mice
H Furusho, M Miyauchi, H Hyogo, T Inubushi… - Journal of …, 2013 - Springer
Background We investigated the effects of dental infection with Porphyromonas gingivalis
(Pg), an important periodontal pathogen, on NASH progression, by feeding mice a high fat …
(Pg), an important periodontal pathogen, on NASH progression, by feeding mice a high fat …
Porphyromonas gingivalis induced periodontitis exacerbates progression of non‐alcoholic steatohepatitis in rats
R Kuraji, H Ito, M Fujita, H Ishiguro… - Clinical and …, 2016 - Wiley Online Library
Non‐alcoholic steatohepatitis (NASH) is a chronic liver disease that can develop into
hepatocirrhosis and hepatic carcinoma. In recent years, epidemiological and animal studies …
hepatocirrhosis and hepatic carcinoma. In recent years, epidemiological and animal studies …
Porphyromonas gingivalis‐derived lipopolysaccharide causes excessive hepatic lipid accumulation via activating NF‐κB and JNK signaling pathways
L Ding, L Liang, Y Zhao, Y Yang, F Liu, Q Ding… - Oral …, 2019 - Wiley Online Library
Background Porphyromonas gingivalis is the main pathogen of periodontal disease
affecting over half of the worldwide adult population. Recent studies have shown that P …
affecting over half of the worldwide adult population. Recent studies have shown that P …
Involvement of a periodontal pathogen, Porphyromonas gingivalis on the pathogenesis of non-alcoholic fatty liver disease
M Yoneda, S Naka, K Nakano, K Wada, H Endo… - BMC …, 2012 - Springer
Background Non-alcoholic fatty liver disease (NAFLD) is a hepatic manifestation of
metabolic syndrome that is closely associated with multiple factors such as obesity …
metabolic syndrome that is closely associated with multiple factors such as obesity …
Involvement of Porphyromonas gingivalis in the progression of non-alcoholic fatty liver disease
T Nakahara, H Hyogo, A Ono, Y Nagaoki… - Journal of …, 2018 - Springer
Background and aims The risk factors in the progression of nonalcoholic fatty liver disease
(NAFLD) have not been fully clarified. Porphyromonas gingivalis (Pg) has been considered …
(NAFLD) have not been fully clarified. Porphyromonas gingivalis (Pg) has been considered …
[HTML][HTML] Porphyromonas gingivalis is a risk factor for the development of nonalcoholic fatty liver disease via ferroptosis
C Yao, D Lan, X Li, Y Wang, S Qi, Y Liu - Microbes and Infection, 2023 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is a metabolic liver disease that can eventually
lead to liver cirrhosis and hepatocellular carcinoma. Porphyromonas gingivalis (Pg) is the …
lead to liver cirrhosis and hepatocellular carcinoma. Porphyromonas gingivalis (Pg) is the …
Porphyromonas gingivalis exacerbates alcoholic liver disease by altering gut microbiota composition and host immune response in mice
Y Gao, P Zhang, Y Wei, C Ye, D Mao… - Journal of Clinical …, 2023 - Wiley Online Library
Aim Porphyromonas gingivalis (P. gingivalis), a major periodontal pathogen, increases the
risk of systemic diseases. P. gingivalis infection is closely associated with alcoholic liver …
risk of systemic diseases. P. gingivalis infection is closely associated with alcoholic liver …
[HTML][HTML] Porphyromonas gingivalis exacerbates the progression of fatty liver disease via CD36-PPARγ pathway
JS Ahn, JW Yang, SJ Oh, YY Shin, MJ Kang… - BMB …, 2021 - ncbi.nlm.nih.gov
Periodontal diseases have been reported to have a multidirectional association with
metabolic disorders. We sought to investigate the correlation between periodontitis and …
metabolic disorders. We sought to investigate the correlation between periodontitis and …
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