Background While kappa free light chain (KFLC) index has become a useful diagnostic
biomarker in multiple sclerosis (MS), its prognostic properties are less explored. B cells play …

Background Evolving evidence suggests that measurement of cerebrospinal fluid (CSF)
kappa free light chain (KFLC) synthesis has high diagnostic sensitivity and specificity for …

Given its highly variable clinical course, an unmet need for objective prognostic assessment
in Multiple Sclerosis (MS) persists. In this work, we suggest that CSF kappa free light chains …

Cerebrospinal kappa free light chain (KFLC)-index is a marker of intrathecal
immunoglobulin synthesis that aids in the diagnosis of multiple sclerosis (MS). However …

Introduction The role of the kappa-free light chain (kFLC) in the diagnosis of multiple
sclerosis (MS) and, to a lesser extent, its role as a medium-term prognostic marker have …

Background Multiple sclerosis (MS) initiates with a first attack or clinically isolated syndrome
(CIS). The importance of an early treatment in MS leads to the search, as soon as possible …

Background Cerebrospinal fluid (CSF) kappa free light chains (KFLC) have been suggested
as quantitative alternative to oligoclonal bands (OB) in multiple sclerosis (MS) diagnosis …

Oligoclonal bands are the gold standard for determination of an intrathecal immunoglobulin
G synthesis and were recently included in the McDonald criteria of 2017 to diagnose …

Background Kappa free light chains (κ-FLC) in the cerebrospinal fluid (CSF) are an
emerging biomarker in multiple sclerosis (MS). Objective To investigate whether κ-FLC …

Background: Kappa free light chains (KFLCs) have been proposed as a diagnostic
biomarker in patients with clinically isolated syndrome (CIS) and multiple sclerosis (MS) …