COVID-19 therapeutics: Clinical application of repurposed drugs and futuristic strategies for target-based drug discovery

S Kumar, M Basu, P Ghosh, U Pal, MK Ghosh - Genes & diseases, 2023 - Elsevier
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causes the complicated
disease COVID-19. Clinicians are continuously facing huge problems in the treatment of …

Drug repurposing for COVID-19: A review and a novel strategy to identify new targets and potential drug candidates

L Rodrigues, R Bento Cunha, T Vassilevskaia… - Molecules, 2022 - mdpi.com
In December 2019, the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2), the causative agent of coronavirus disease 2019 (COVID-19) was first identified in the …

Drug discovery by drug repurposing: combating COVID-19 in the 21st century

N Sanghai, K Shafiq, GK Tranmer - Mini Reviews in Medicinal …, 2021 - ingentaconnect.com
Due to the rapidly developing nature of the current COVID-19 outbreak and its almost
immediate humanitarian and economic toll, coronavirus drug discovery efforts have largely …

Progress, pitfalls, and path forward of drug repurposing for COVID-19 treatment

NS Taibe, MA Kord, MA Badawy… - Therapeutic …, 2022 - journals.sagepub.com
On 30 January 2020, the World Health Organization (WHO) declared the novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic a public health emergency of …

Therapeutic effectiveness and safety of repurposing drugs for the treatment of COVID-19: position standing in 2021

S Alam, TB Kamal, MMR Sarker, JR Zhou… - Frontiers in …, 2021 - frontiersin.org
COVID-19, transmitted by SARS-CoV-2, is one of the most serious pandemic situations in
the history of mankind, and has already infected a huge population across the globe. This …

Clinical features and mechanistic insights into drug repurposing for combating COVID-19

P Asrani, K Tiwari, MS Eapen, KD McAlinden… - … International Journal of …, 2022 - Elsevier
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emerged from Wuhan in
China before it spread to the entire globe. It causes coronavirus disease of 2019 (COVID-19) …

Revisiting potential druggable targets against SARS‐CoV‐2 and repurposing therapeutics under preclinical study and clinical trials: A comprehensive review

AAM Sohag, MA Hannan, S Rahman… - Drug development …, 2020 - Wiley Online Library
Abstract Coronavirus disease‐19 (COVID‐19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2), is one of the most contagious diseases in human …

Drugs repurposing for SARS-CoV-2: new insight of COVID-19 druggability

SK Debnath, M Debnath, R Srivastava… - Expert Review of Anti …, 2022 - Taylor & Francis
Introduction The ongoing epidemic of severe acute respiratory syndrome coronavirus-2
(SARS-CoV-2) creates a massive panic worldwide due to the absence of effective …

[HTML][HTML] Therapeutics for COVID-19 and post COVID-19 complications: An update

D Basu, VP Chavda, AA Mehta - Current Research in Pharmacology and …, 2022 - Elsevier
Since its inception in late December 2020 in China, novel coronavirus has affected the
global socio-economic aspect. Currently, the world is seeking safe and effective treatment …

[HTML][HTML] The drug repurposing for COVID-19 clinical trials provide very effective therapeutic combinations: lessons learned from major clinical studies

C Chakraborty, AR Sharma, M Bhattacharya… - Frontiers in …, 2021 - frontiersin.org
SARS-CoV-2 has spread across the globe in no time. In the beginning, people suffered due
to the absence of efficacious drugs required to treat severely ill patients. Nevertheless, still …