[HTML][HTML] No laughing white matter: Reduced integrity of the cortical cholinergic pathways in Parkinson's disease-related cognitive impairment
RA Crockett, KB Wilkins, S Aditham… - Neurobiology of …, 2023 - Elsevier
Background Approximately one third of recently diagnosed Parkinson's disease (PD)
patients experience cognitive decline. The nucleus basalis of Meynert (NBM) degenerates …
patients experience cognitive decline. The nucleus basalis of Meynert (NBM) degenerates …
Nucleus basalis of Meynert degeneration predicts cognitive impairment in Parkinson's disease
H Wilson, ER de Natale, M Politis - Handbook of Clinical Neurology, 2021 - Elsevier
Abstract Cognitive impairment affects approximately 20%–50% of patients with Parkinson's
disease (PD), with a higher prevalence as the disease advances. The nucleus basalis of …
disease (PD), with a higher prevalence as the disease advances. The nucleus basalis of …
Nucleus basalis of Meynert degeneration precedes and predicts cognitive impairment in Parkinson's disease
J Schulz, G Pagano, JA Fernández Bonfante, H Wilson… - Brain, 2018 - academic.oup.com
Currently, no reliable predictors of cognitive impairment in Parkinson's disease exist. We
hypothesized that microstructural changes at grey matter T1-weighted MRI and diffusion …
hypothesized that microstructural changes at grey matter T1-weighted MRI and diffusion …
[HTML][HTML] Meynert nucleus-related cortical thinning in Parkinson's disease with mild cognitive impairment
S Rong, Y Li, B Li, K Nie, P Zhang, T Cai… - … Imaging in Medicine …, 2021 - ncbi.nlm.nih.gov
Background Cognitive impairment in Parkinson's disease (PD) involves the cholinergic
system and cholinergic neurons, especially the nucleus basalis of Meynert (NBM/Ch4) …
system and cholinergic neurons, especially the nucleus basalis of Meynert (NBM/Ch4) …
[HTML][HTML] Longitudinal degeneration of the basal forebrain predicts subsequent dementia in Parkinson's disease
Objectives Cholinergic dysfunction plays a prominent role in cognitive impairment in
Parkinson's disease (PD). The aim of this study was to assess the relationship of baseline …
Parkinson's disease (PD). The aim of this study was to assess the relationship of baseline …
Lower volume, more impairment: reduced cholinergic basal forebrain grey matter density is associated with impaired cognition in Parkinson disease
MJ Barrett, SA Sperling, JC Blair… - Journal of Neurology …, 2019 - jnnp.bmj.com
Objective A major contributor to dementia in Parkinson disease (PD) is degeneration of the
cholinergic basal forebrain. This study determined whether cholinergic nucleus 4 (Ch4) …
cholinergic basal forebrain. This study determined whether cholinergic nucleus 4 (Ch4) …
In vivo cholinergic basal forebrain atrophy predicts cognitive decline in de novo Parkinson's disease
Abstract See Gratwicke and Foltynie (doi: 10.1093/brain/awx333) for a scientific commentary
on this article. Cognitive impairments are a prevalent and disabling non-motor complication …
on this article. Cognitive impairments are a prevalent and disabling non-motor complication …
[HTML][HTML] In vivo cholinergic basal forebrain degeneration and cognition in Parkinson's disease: Imaging results from the COPPADIS study
MJ Grothe, MA Labrador-Espinosa, S Jesús… - Parkinsonism & Related …, 2021 - Elsevier
Introduction We aimed to assess associations between multimodal neuroimaging measures
of cholinergic basal forebrain (CBF) integrity and cognition in Parkinson's disease (PD) …
of cholinergic basal forebrain (CBF) integrity and cognition in Parkinson's disease (PD) …
Frontostriatal and limbic contributions to cognitive decline in Parkinson's disease
Abstract Background and Purpose The circuitry underlying heterogenous cognitive profiles
in Parkinson's disease (PD) remains unclear. The purpose of this study is to investigate …
in Parkinson's disease (PD) remains unclear. The purpose of this study is to investigate …
Early nucleus basalis of Meynert degeneration predicts cognitive decline in Parkinson's disease
JP Gratwicke, T Foltynie - Brain, 2018 - academic.oup.com
Early nucleus basalis of Meynert degeneration predicts cognitive decline in Parkinson’s disease
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