Fruit and vegetable polyphenols as natural bioactive inhibitors of pancreatic lipase and cholesterol esterase: Inhibition mechanisms, polyphenol influences …

X He, L Chen, Y Pu, H Wang, J Cao, W Jiang - Food Bioscience, 2023 - Elsevier
Pancreatic lipase and cholesterol esterase are key enzymes in the lipid digestion and
absorption pathway and are also targeted for control in response to obesity and other …

Mode of pancreatic lipase inhibition activity in vitro by some flavonoids and non-flavonoid polyphenols

ATMA Rahim, Y Takahashi, K Yamaki - Food Research International, 2015 - Elsevier
Numerous reports have shown plant metabolites as potential inhibitors of pancreatic lipase
(PL). The most notable group is plant polyphenols. However, a limited number of reports …

[HTML][HTML] Polyphenolic compounds as pancreatic lipase inhibitors

T Buchholz, MF Melzig - Planta medica, 2015 - thieme-connect.com
Obesity and its associated diseases such as diabetes mellitus and coronary heart diseases
are a major challenge for our society. An important target for the treatment of obesity …

Inhibitory effects of oolong tea polyphenols on pancreatic lipase in vitro

M Nakai, Y Fukui, S Asami, Y Toyoda-Ono… - Journal of agricultural …, 2005 - ACS Publications
Fifty-four polyphenols isolated from tea leaves were evaluated for their inhibitory activities
against pancreatic lipase, the key enzyme of lipid absorption in the gut.(−)-Epigallocatechin …

Berry polyphenols inhibit pancreatic lipase activity in vitro

GJ McDougall, NN Kulkarni, D Stewart - Food Chemistry, 2009 - Elsevier
Polyphenol-rich extracts from a range of berries were tested for their ability to inhibit
pancreatic lipase activity in vitro. Blackcurrant and rowan extracts had no effect, blueberry …

Inhibitory effect of black chokeberry fruit polyphenols on pancreatic lipase–Searching for most active inhibitors

D Sosnowska, A Podsędek, M Redzynia… - Journal of Functional …, 2018 - Elsevier
In this study, the effects of a chokeberry fruit crude extract (CE), its ethyl acetate fractions
(EAF7 & EAF2) and a polyphenol-rich fraction (PRF) on esterase and lipolytic activities of …

[PDF][PDF] In vitro inhibition of pancreatic lipase by polyphenols: a kinetic, fluorescence spectroscopy and molecular docking study.

AI Martinez-Gonzalez, E Alvarez-Parrilla… - 2017 - hrcak.srce.hr
The inhibitory activity and binding characteristics of caffeic acid, p-coumaric acid, quercetin
and capsaicin, four phenolic compounds found in hot pepper, against porcine pancreatic …

Inhibition of pancreatic lipase by coffee leaves-derived polyphenols: A mechanistic study

Q Cao, S Mei, A Mehmood, Y Sun, X Chen - Food Chemistry, 2024 - Elsevier
The suppression of pancreatic lipase has been employed to mitigate obesity. This study
explored the mechanism of coffee leaf extracts to inhibit pancreatic lipase. The ethyl acetate …

Oligomeric procyanidins in apple polyphenol are main active components for inhibition of pancreatic lipase and triglyceride absorption

H Sugiyama, Y Akazome, T Shoji… - Journal of agricultural …, 2007 - ACS Publications
Inhibitory effects of apple polyphenol extract (AP) and procyanidin contained in AP on in
vitro pancreatic lipase activity and in vivo triglyceride absorption in mice and humans were …

[HTML][HTML] Separation, characterization and mammal pancreatic lipase inhibitory potential of cucumber flower flavonoids

DN Olennikov - Separations, 2023 - mdpi.com
Edible flowers are a new “old” trend in modern gastronomy and healthy nutrition aimed at
increasing food attractiveness and improving the consumption of beneficial …