Metabolism of oxygen by cells generates potentially deleterious reactive oxygen species
(ROS). Under normal conditions the rate and magnitude of oxidant formation is balanced by …

Hypertension is associated with an elevation of reactive oxygen species (ROS) and
frequently also with an impairment of endogenous antioxidant mechanisms. Experimental …

Metabolism of oxygen by cells generates potentially deleterious reactive oxygen species,
including superoxide anion radical, hydrogen peroxide, and hydroxyl radical. Under normal …

Background: Disruption of redox signaling is a common pathophysiological mechanism
observed in several diseases. In hypertension, oxidative stress, resulted either from …

Significance: Reactive oxygen species (ROS) are signaling molecules that are important in
physiological processes, including host defense, aging, and cellular homeostasis. Increased …

Mammalian cells are capable of generating metabolites of oxygen, referred to as reactive
oxygen species (ROS) via the action of several enzymes. In vascular cells, ROS are …

Hypertension is a major contributor to the development of renal failure, cardiovascular
disease, and stroke. These pathologies are associated with vascular functional and …

Hypertension is a major cardiovascular risk factor. Of the many processes involved in the
pathophysiology of hypertension, vascular damage due to oxidative stress (excess …

Reactive oxygen species (ROS), including superoxide (· O 2−), hydrogen peroxide (H 2 O 2),
and hydroxyl anion (OH-), and reactive nitrogen species, such as nitric oxide (NO) and …

Many factors have been implicated in the pathophysiology of hypertension such as
upregulation of the renin-angiotensin-aldosterone system, activation of the sympathetic …