Vertebrates have some of the most complex and diverse features in animals, from varied
craniofacial morphologies to colorful pigmentation patterns and elaborate social behaviors …

In the vertebrate embryo, multiple cell types originate from a common structure, the neural
crest (NC), which forms at the dorsal tips of the neural epithelium. The NC gives rise to …

Vertebrates possess lineage-specific characteristics. These include paired anterior sense
organs and a robust, modular head skeleton built of cellular cartilage and bone. All of these …

As vertebrates evolved from protochordates, they shifted to a more predatory lifestyle, and
radiated and adapted to most niches of the planet. This process was largely facilitated by the …

Summary cis-regulatory changes play a central role in morphological divergence, yet the
regulatory principles underlying emergence of human traits remain poorly understood. Here …

In the vertebrate embryo, the neural crest forms transiently in the dorsal neural primordium to
yield migratory cells that will invade nearly all tissues and later, will differentiate into bones …

Since the discovery of this cell population by His in 1850, the neural crest has been under
intense study for its important role during vertebrate development. Much has been learned …

The neural crest is a fascinating embryonic population unique to vertebrates that is endowed
with remarkable differentiation capacity. Thought to originate from ectodermal tissue, neural …

Neural crest cells (NCCs) comprise a multipotent, migratory cell population that generates a
diverse array of cell and tissue types during vertebrate development. These include cartilage …

The neural crest is a vertebrate-specific embryonic stem cell population that gives rise to a
vast array of cell types throughout the animal body plan. These cells are first born at the …