For bone defect repair, it is critical to utilize biomaterials with pro‐angiogenic properties to
enhance osteogenesis. Hydroxyapatite (HA)‐based materials widely used in clinical …

Magnesium alloys with coatings have the potential to be used for bone substitute
alternatives since their mechanical properties are close to those of human bone. However …

Biodegradation and bioinductivity are important factors to decide scaffold efficiency in
inducing tissue regeneration. For bone regeneration, calcium silicate (CS) is attractive for its …

Osteogenesis is closely complemented by angiogenesis during the bone regeneration
process. The development of functional hydrogel bone substitutes that mimic the …

Critical-size bone defects are an important problem in clinical practice, which usually occurs
in severe trauma, or tumor resection, and cannot heal completely and autonomously …

Abstract Magnesium cation (Mg 2+) has been an emerging therapeutic agent for inducing
vascularized bone regeneration. However, the therapeutic effects of current magnesium …

Multifunctional biomaterials that simultaneously combine high biocompatibility,
biodegradability, and bioactivity are promising for applications in various biomedical fields …

In this work, we focus on the in vitro and in vivo response of composite scaffolds obtained by
incorporating Mg, CO3‐doped hydroxyapatite (HA) particles in poly (ε‐caprolactone)(PCL) …

Varying degrees of hydroxyapatite (HA) surface functionalization have been implicated as
the primary driver of differential osteogenesis observed in infiltrating cells. The ability to …

Promoting angiogenesis is a key strategy for stimulating the repair of damaged tissues,
including bone. Among other proangiogenic factors, ions have recently been considered a …