A role for novel adipose tissue‐secreted factors in obesity‐related carcinogenesis

B Cabia, S Andrade, MC Carreira… - Obesity …, 2016 - Wiley Online Library
Obesity, a pandemic disease, is caused by an excessive accumulation of fat that can have
detrimental effects on health. Adipose tissue plays a very important endocrine role, secreting …

Adipose tissue, obesity and adipokines: role in cancer promotion

A Booth, A Magnuson, J Fouts… - … molecular biology and …, 2015 - degruyter.com
Adipose tissue is a complex organ with endocrine, metabolic and immune regulatory roles.
Adipose depots have been characterized to release several adipocytokines that work locally …

Tumor metabolic reprogramming by adipokines as a critical driver of obesity-associated cancer progression

DV Pham, PH Park - International journal of molecular sciences, 2021 - mdpi.com
Adiposity is associated with an increased risk of various types of carcinoma. One of the
plausible mechanisms underlying the tumor-promoting role of obesity is an aberrant …

[HTML][HTML] Role of obesity-associated dysfunctional adipose tissue in cancer: a molecular nutrition approach

PL Prieto-Hontoria, P Pérez-Matute… - … et Biophysica Acta (BBA …, 2011 - Elsevier
Obesity is a complex disease caused by the interaction of a myriad of genetic, dietary,
lifestyle and environmental factors, which favors a chronic positive energy balance, leading …

Leptin: A heavyweight player in obesity-related cancers

A Caruso, L Gelsomino, S Panza, FM Accattatis… - Biomolecules, 2023 - mdpi.com
Obesity, defined as the abnormal or excessive expansion of white adipose tissue, has
reached pandemic proportions and is recognized as an important health concern since it is …

Adipose tissue, obesity and adiponectin: role in endocrine cancer risk

A Tumminia, F Vinciguerra, M Parisi… - International journal of …, 2019 - mdpi.com
Adipose tissue has been recognized as a complex organ with endocrine and metabolic
roles. The excess of fat mass, as occurs during overweight and obesity states, alters the …

Obesity and cancer: the role of dysfunctional adipose tissue

RCM Van Kruijsdijk, E Van Der Wall… - … , biomarkers & prevention, 2009 - AACR
Overweight and obesity are health problems of epidemic proportions, increasing the risk not
only of cardiovascular disease and type 2 diabetes mellitus but also of various types of …

Classic and novel adipocytokines at the intersection of obesity and cancer: diagnostic and therapeutic strategies

N Spyrou, KI Avgerinos, CS Mantzoros… - Current obesity …, 2018 - Springer
Abstract Purpose of Review In this review, we investigate the role of classic and novel
adipocytokines in cancer pathogenesis synopsizing the mechanisms underlying the …

The emerging role of adiponectin in female malignancies

L Gelsomino, GD Naimo, S Catalano, L Mauro… - International Journal of …, 2019 - mdpi.com
Obesity, characterized by excess body weight, is now accepted as a hazardous health
condition and an oncogenic factor. In different epidemiological studies obesity has been …

Leptin and Adiponectin: new players in the field of tumor cell and leukocyte migration

K Lang, J Ratke - Cell Communication and Signaling, 2009 - Springer
Adipose tissue is no longer considered to be solely an energy storage, but exerts important
endocrine functions, which are primarily mediated by a network of various soluble factors …