Virtual Cell modelling and simulation software environment

II Moraru, JC Schaff, BM Slepchenko, ML Blinov… - IET systems biology, 2008 - IET
The Virtual Cell (VCell; http://vcell. org/) is a problem solving environment, built on a central
database, for analysis, modelling and simulation of cell biological processes. VCell …

The Virtual Cell: a software environment for computational cell biology

LM Loew, JC Schaff - TRENDS in Biotechnology, 2001 - cell.com
The newly emerging field of computational cell biology requires software tools that address
the needs of a broad community of scientists. Cell biological processes are controlled by an …

Virtual Cell: computational tools for modeling in cell biology

DC Resasco, F Gao, F Morgan, IL Novak… - … Systems Biology and …, 2012 - Wiley Online Library
Abstract The Virtual Cell (VCell) is a general computational framework for modeling
physicochemical and electrophysiological processes in living cells. Developed by the …

Morpheus: a user-friendly modeling environment for multiscale and multicellular systems biology

J Starruß, W De Back, L Brusch, A Deutsch - Bioinformatics, 2014 - academic.oup.com
Morpheus is a modeling environment for the simulation and integration of cell-based models
with ordinary differential equations and reaction-diffusion systems. It allows rapid …

[HTML][HTML] STEPS: efficient simulation of stochastic reaction–diffusion models in realistic morphologies

I Hepburn, W Chen, S Wils, E De Schutter - BMC systems biology, 2012 - Springer
Background Models of cellular molecular systems are built from components such as
biochemical reactions (including interactions between ligands and membrane-bound …

Physiological modeling with virtual cell framework

JC Schaff, BM Slepchenko, LM Loew - Methods in enzymology, 2000 - Elsevier
This article describes a computational framework for cell biological modeling and simulation
that is based on the mapping of experimental biochemical and electrophysiological data …

A cell-based simulation software for multi-cellular systems

S Hoehme, D Drasdo - Bioinformatics, 2010 - academic.oup.com
CellSys is a modular software tool for efficient off-lattice simulation of growth and
organization processes in multi-cellular systems in 2D and 3D. It implements an agent …

The virtual cell

J Schaff, LM Loew - Biocomputing'99, 1999 - World Scientific
This paper describes a computational framework for cell biological modeling and simulation
that is based on the mapping of experimental biochemical andelectrophysiological data onto …

Cellware—a multi-algorithmic software for computational systems biology

P Dhar, TC Meng, S Somani, L Ye, A Sairam… - …, 2004 - academic.oup.com
The intracellular environment of a cell hosts a wide variety of enzymatic reactions, diffusion
events, molecular binding, polymerization and metabolic channeling. To transform these …

Whole-cell simulation: a grand challenge of the 21st century

M Tomita - TRENDS in Biotechnology, 2001 - cell.com
Study of the cell will never be complete unless its dynamic behavior is understood. The
complex behavior of the cell cannot be determined or predicted unless a computer model of …