[HTML][HTML] Immunological roles of NLR in allergic diseases and its underlying mechanisms

MSM Tsang, T Hou, BCL Chan, CK Wong - International journal of …, 2021 - mdpi.com
Our understanding on the immunological roles of pathogen recognition in innate immunity
has vastly increased over the past 20 years. Nucleotide-binding oligomerization domain …

[HTML][HTML] NOD-like receptors in asthma

D Alvarez-Simon, S Ait Yahia, P De Nadai… - Frontiers in …, 2022 - frontiersin.org
Asthma is an extremely prevalent chronic inflammatory disease of the airway where innate
and adaptive immune systems participate collectively with epithelial and other structural …

NOD-like receptors: ancient sentinels of the innate immune system

P Rosenstiel, G Jacobs, A Till, S Schreiber - Cellular and Molecular Life …, 2008 - Springer
NOD-like receptors (NLRs) comprise a family of cytosolic proteins that have been implicated
as ancient cellular sentinels mediating protective immune responses elicited by intracellular …

[HTML][HTML] NOD-like receptors: Guards of cellular homeostasis perturbation during infection

G Pei, A Dorhoi - International journal of molecular sciences, 2021 - mdpi.com
The innate immune system relies on families of pattern recognition receptors (PRRs) that
detect distinct conserved molecular motifs from microbes to initiate antimicrobial responses …

TLRs, NLRs and RLRs: innate sensors and their impact on allergic diseases–a current view

H Heine - Immunology letters, 2011 - Elsevier
Charles Janeway first wrote 1989 about how important recognition of “certain characteristics
or patterns common on infectious agents but absent from the host” would be for our immune …

Understanding the regulation of pattern recognition receptors in inflammatory diseases–a 'Nod'in the right direction

CL Feerick, DP McKernan - Immunology, 2017 - Wiley Online Library
Nucleotide‐binding oligomerization domain (NOD)‐like receptors (NLR s) are a family of 23
receptors known as pattern recognition receptors; they are expressed in many cell types and …

[HTML][HTML] Nod-like receptors in host defence and disease at the epidermal barrier

J Danis, M Mellett - International Journal of Molecular Sciences, 2021 - mdpi.com
The nucleotide-binding domain and leucine-rich-repeat-containing family
(NLRs)(sometimes called the NOD-like receptors, though the family contains few bona fide …

[HTML][HTML] Activation and regulation mechanisms of NOD-like receptors based on structural biology

U Ohto - Frontiers in Immunology, 2022 - frontiersin.org
Innate immunity is a primary defense system against microbial infections. Innate immune
pattern recognition receptors (PRRs) play pivotal roles in detection of invading pathogens …

[PDF][PDF] Regulation of the antimicrobial response by NLR proteins

E Elinav, T Strowig, J Henao-Mejia, RA Flavell - Immunity, 2011 - cell.com
Nucleotide-binding, oligomerization domain (NOD)-like receptor (NLR) proteins are a family
of innate immune receptors that play a pivotal role in microbial sensing, leading to the …

NOD-like receptors mediated activation of eosinophils interacting with bronchial epithelial cells: a link between innate immunity and allergic asthma

CK Wong, S Hu, KML Leung, J Dong, L He… - Cellular & molecular …, 2013 - nature.com
Key intracytosolic pattern recognition receptors of innate immunity against bacterial
infections are nucleotide-binding oligomerization domain (NOD)-like receptors (NLRs). We …