Resveratrol supplement inhibited the NF-κB inflammation pathway through activating AMPKα-SIRT1 pathway in mice with fatty liver

Y Tian, J Ma, W Wang, L Zhang, J Xu, K Wang… - Molecular and cellular …, 2016 - Springer
Nonalcoholic fatty liver disease (NAFLD) is characterized by high levels of nonesterified fatty
acids (NEFA), inflammation, and hepatic steatosis. Inflammation plays a crucial role in the …

Resveratrol improves non-alcoholic fatty liver disease by activating AMP-activated protein kinase

J Shang, L Chen, F Xiao, H Sun, H Ding… - Acta Pharmacologica …, 2008 - nature.com
Aim: To investigate whether resveratrol (RSV) can improve non-alcoholic fatty liver disease
(NAFLD) and to find the possible mechanism. Methods: Rats fed a high-fat diet were treated …

Vitamin D3 alleviates nonalcoholic fatty liver disease in rats by inhibiting hepatic oxidative stress and inflammation via the SREBP-1-c/PPARα-NF-κB/IR-S2 signaling …

D Reda, GE Elshopakey, TA Albukhari… - Frontiers in …, 2023 - frontiersin.org
Introduction: Nonalcoholic fatty liver disease (NAFLD) is a chronic disease characterized by
fat deposits in liver cells, which can lead to hepatitis and fibrosis. This study attempted to …

Resveratrol modulates autophagy and NF-κB activity in a murine model for treating non-alcoholic fatty liver disease

L Li, J Hai, Z Li, Y Zhang, H Peng, K Li… - Food and Chemical …, 2014 - Elsevier
In this study, we aimed to investigate the therapeutic effects and involved mechanisms of
resveratrol on an established non-alcoholic fatty liver disease (NAFLD) murine model. Wild …

[HTML][HTML] Resveratrol attenuates hepatic steatosis in high-fat fed mice by decreasing lipogenesis and inflammation

JMO Andrade, AF Paraíso, MVM de Oliveira… - Nutrition, 2014 - Elsevier
Objective Resveratrol (RSV) is the most studied natural compound that activates sirtuins,
which produce beneficial metabolic effects on lipid and glucose metabolism. The aim of the …

Salidroside attenuates high‐fat diet‐induced nonalcoholic fatty liver disease via AMPK‐dependent TXNIP/NLRP3 pathway

T Zheng, X Yang, W Li, Q Wang, L Chen… - Oxidative medicine …, 2018 - Wiley Online Library
Our previous studies suggested that salidroside could alleviate hepatic steatosis in type 2
diabetic C57BLKS/Leprdb (db/db) mice. The aim of the present study was to evaluate the …

Sinapine reduces non-alcoholic fatty liver disease in mice by modulating the composition of the gut microbiota

Y Li, J Li, Q Su, Y Liu - Food & Function, 2019 - pubs.rsc.org
Non-alcoholic fatty liver disease (NAFLD) is associated with low-grade chronic inflammation
and intestinal dysbiosis. In this study, we investigated the potential benefits of sinapine, a …

SIRT1/NFκB pathway mediates anti-inflammatory and anti-apoptotic effects of rosmarinic acid on in a mouse model of nonalcoholic steatohepatitis (NASH)

T Komeili-Movahhed, M Bassirian… - Journal of Receptors …, 2022 - Taylor & Francis
Nonalcoholic steatohepatitis (NASH) is considered as a common liver disease. SIRT1, a
pivotal sensor, controls activation of metabolic, inflammatory and apoptotic pathways …

Hesperetin ameliorates hepatic oxidative stress and inflammation via the PI3K/AKT-Nrf2-ARE pathway in oleic acid-induced HepG2 cells and a rat model of high-fat …

J Li, T Wang, P Liu, F Yang, X Wang, W Zheng… - Food & function, 2021 - pubs.rsc.org
Non-alcoholic fatty liver disease (NAFLD) is considered the most common liver disease.
Dietary supplementation has become a promising strategy for managing NAFLD …

Daucosterol Alleviates Alcohol− Induced Hepatic Injury and Inflammation through P38/NF− κB/NLRP3 Inflammasome Pathway

F Zhang, M Wang, Y Zha, J Zhou, J Han, S Zhang - Nutrients, 2023 - mdpi.com
Alcoholic liver disease (ALD) is caused by chronic excessive alcohol consumption, which
leads to inflammation, oxidative stress, lipid accumulation, liver fibrosis/cirrhosis, and even …