Background More than 80% of advanced prostate cancer (PCa) cases have bone
metastasis, with a 5-year survival rate of 25%. Previously, we reported that GRT, a …

Background Androgen ablation therapy is the primary treatment for metastatic prostate
cancer (PCa). However, the majority of PCa patients receiving the androgen deprivation …

Enzalutamide, a nonsteroidal antiandrogen, significantly prolonged the survival of patients
with metastatic castration-resistant prostate cancer (CRPC). However, patients receiving …

Prostate cancer metastasis is associated with poor prognosis and is difficult to treat clinically.
Numerous studies have shown that Asiatic Acid (AA) has antibacterial, anti-inflammatory …

Here we showed that Osthole, 7-methoxy-8-(3-methyl-2-butenyl) coumarin, a bioactive
coumarin derivative extracted from medicinal plants, inhibited migration, invasion, epithelial …

BACKGROUND: Prostate cancer (PCa) is one of the most common malignancies in men.
PCa is difficult to detect in its early stages, and most patients are diagnosed in the middle to …

PC-SPES is an eight-herb mixture that has an activity against prostate cancer. Recently, we
purified Saw Palmetto (Serenoa repens) from PC-SPES and found that Saw Palmetto …

Androgen deprivation therapy is the gold standard regimen for advanced Prostate cancer
(PCa) patients, nevertheless, patients eventually develop into castration-resistant prostate …

Saussurea lappa has been used in Chinese traditional medicine for the treatment of
abdominal pain, tenesmus, nausea, and cancer; previous studies have shown that S. lappa …

The protein kinase Akt plays an important role in cell proliferation and survival in many
cancers, including prostate cancer. Due to its kinase activity, it serves as a molecular conduit …