Ketogenesis and ketolysis are central metabolic processes activated during the response to
fasting. Ketogenesis is regulated in multiple stages, and a nuclear receptor peroxisome …

Ketogenesis is the branch of mammalian metabolism concerned with the synthesis of ketone
bodies. In this process, the small, water-soluble compounds acetoacetate, D-3-β …

Ketone bodies are traditionally viewed as metabolic substrates in carbohydrate restriction
and are applied in the treatment of epilepsy and other neurodegenerative diseases …

This review outlines the molecular sensors that reprogram cellular metabolism in response
to the ketogenic diet (KD). Special emphasis is placed on the fasting-, fatty acid-and drug …

The ketone bodies (KBs) β-hydroxybutyrate and acetoacetate are important alternative
energy sources for glucose during nutrient deprivation. KBs synthesized by hepatic …

Ketone bodies are metabolites that replace glucose as the main fuel of the brain in situations
of glucose scarcity, including prolonged fasting, extenuating exercise, or pathological …

Mitochondria are the energy-producing organelles of the cell, generating ATP via oxidative
phosphorylation mainly by using pyruvate derived from glycolytic processing of glucose …

Ketone bodies (KBs), comprising β-hydroxybutyrate, acetoacetate and acetone, are a set of
fuel molecules serving as an alternative energy source to glucose. KBs are mainly produced …

Under normal physiological conditions the brain primarily utilizes glucose for ATP
generation. However, in situations where glucose is sparse, eg, during prolonged fasting …

Ketone bodies are small compounds derived from fatty acids that behave as an alternative
mitochondrial energy source when insulin levels are low, such as during fasting or …