Degradation of Exogenous Fatty Acids in Escherichia coli

V Pavoncello, F Barras, E Bouveret - Biomolecules, 2022 - mdpi.com
Many bacteria possess all the machineries required to grow on fatty acids (FA) as a unique
source of carbon and energy. FA degradation proceeds through the β-oxidation cycle that …

[HTML][HTML] Matching the β-oxidation gene repertoire with the wide diversity of fatty acids

V Schiaffi, F Barras, E Bouveret - Current Opinion in Microbiology, 2024 - Elsevier
Bacteria can use fatty acids (FAs) from their environment as carbon and energy source. This
catabolism is performed by the enzymes of the well-known β-oxidation machinery …

A molecular view of fatty acid catabolism in Escherichia coli

WD Nunn - Microbiological reviews, 1986 - Am Soc Microbiol
Gram-negative bacteria such as Escherichia coli can utilize fatty acids and acetate as sole
carbon and energy sources (30, 51, 76). After entry into the cell, fatty acids are either …

Molecular inroads into the regulation and metabolism of fatty acids, lessons from bacteria

CC DiRusso, PN Black, JD Weimar - Progress in Lipid Research, 1999 - Elsevier
5.4. Genetic and biochemical characterization of fatty acyl CoA synthetase 165 5.5.
Evidence for additional protein components in the Class I fatty acid transport system 171 6 …

Reassessment of the genetic regulation of fatty acid synthesis in Escherichia coli: global positive control by the dual functional regulator FadR

L My, N Ghandour Achkar, JP Viala… - Journal of …, 2015 - Am Soc Microbiol
ABSTRACT In Escherichia coli, the FadR transcriptional regulator represses the expression
of fatty acid degradation (fad) genes. However, FadR is also an activator of the expression of …

Metabolic flux between unsaturated and saturated fatty acids is controlled by the FabA: FabB ratio in the fully reconstituted fatty acid biosynthetic pathway of …

X Xiao, X Yu, C Khosla - Biochemistry, 2013 - ACS Publications
The entire fatty acid biosynthetic pathway of Escherichia coli, starting from the acetyl-CoA
carboxylase, has been reconstituted in vitro from 14 purified protein components …

The β-Oxidation Systems of Escherichia coli and Salmonella enterica Are Not Functionally Equivalent

SH Iram, JE Cronan - Journal of bacteriology, 2006 - Am Soc Microbiol
Based on its genome sequence, the pathway of β-oxidative fatty acid degradation in
Salmonella enterica serovar Typhimurium LT2 has been thought to be identical to the well …

Formation of fatty acids

IM López-Lara, O Geiger - Handbook of hydrocarbon and lipid …, 2010 - infona.pl
Fatty acids are the building blocks of diverse membrane lipids and therefore are essential for
the viability of all cells, except the Archaea where side chains of membrane lipids are …

FadD is required for utilization of endogenous fatty acids released from membrane lipids

A Pech-Canul, J Nogales, A Miranda-Molina… - Journal of …, 2011 - Am Soc Microbiol
FadD is an acyl coenzyme A (CoA) synthetase responsible for the activation of exogenous
long-chain fatty acids (LCFA) into acyl-CoAs. Mutation of fadD in the symbiotic nitrogen …

Escherichia coli FadR Positively Regulates Transcription of the fabB Fatty Acid Biosynthetic Gene

JW Campbell, JE Cronan Jr - Journal of bacteriology, 2001 - Am Soc Microbiol
In Escherichia coli expression of the genes of fatty acid degradation (fad) is negatively
regulated at the transcriptional level by FadR protein. In contrast the unsaturated fatty acid …