Hepatotoxicity‐related issues are poorly predicted during preclinical experimentation, as its
relevance is limited by the inadequacy to screen all the non‐physiological subclasses of the …

Bioprinting is a key technique to fabricate cell-laden volumetric constructs with controlled
geometry. It can be used not only to replicate the architecture of a target organ but also to …

Bioengineering an in vitro liver model recapitulating the native liver microarchitecture
consisting of parenchymal and non-parenchymal cells is crucial in achieving cellular …

Three-dimensional (3D) bioprinting is a promising technology to establish a 3D in vitro
hepatic model that holds great potential in toxicological evaluation. However, in current …

Liver tissue engineering offers a remarkable tool for toxicological screening and an
approach to disease modeling, and provides an alternative solution to liver transplantation …

Drug-induced hepatotoxicity is a leading cause of clinical trial withdrawal. Therefore, in vitro
modeling the hepatic behavior and functionalities is not only crucial to better understand …

Current 3D printing of tissue is restricted by the use of biomaterials that do not recapitulate
the native properties of the extracellular matrix (ECM). These restrictions have thus far …

With the aim of understanding and recapitulating cellular interactions of hepatocytes in their
physiological microenvironment and to generate an artificial 3D in vitro model, a co-culture …

Although lipid‐based formulations are an attractive approach for enhancing the oral
bioavailability of lipophilic drugs, their addition into solid oral dosage forms has been proven …

Bioprinted liver organoids (LOs) have emerged as a crucial tool for investigating patient-
specific models and enhancing disease comprehension as well as overall patient care …