[HTML][HTML] Ant-Neointimal Formation Effects of SLC6A6 in Preventing Vascular Smooth Muscle Cell Proliferation and Migration via Wnt/β-Catenin Signaling
Z Rong, F Li, R Zhang, S Niu, X Di, L Ni… - International Journal of …, 2023 - mdpi.com
Vascular smooth muscle cells (VSMCs) play an important role in the pathogenesis of
vascular remolding, such as atherosclerosis and restenosis. Solute carrier family 6 member …
vascular remolding, such as atherosclerosis and restenosis. Solute carrier family 6 member …
NLRC5 modulates phenotypic transition and inflammation of human venous smooth muscle cells by activating Wnt/β-catenin pathway via TLR4 in varicose veins
T Fang, S Sun, B Zhao, J Dong, K Cao, W Wang - Microvascular Research, 2022 - Elsevier
In varicose veins, abnormal phenotypic transition and inflammatory response is commonly
found in venous smooth muscle cells (VSMCs). We aimed to explore the potential role and …
found in venous smooth muscle cells (VSMCs). We aimed to explore the potential role and …
Wnt5a/Ror2 promotes vascular smooth muscle cells proliferation via activating PKC
Y Shi, H Li, J Gu, Y Gong, X Xie… - Folia Histochemica et …, 2022 - journals.viamedica.pl
Introduction. Abnormal proliferation of vascular smooth muscle cells (VSMCs) can cause
various vascular diseases, such as atherosclerosis, restenosis, and pulmonary …
various vascular diseases, such as atherosclerosis, restenosis, and pulmonary …
[HTML][HTML] WNT11-conditioned medium promotes angiogenesis through the activation of non-canonical WNT-PKC-JNK signaling pathway
J Wang, M Gong, S Zuo, J Xu, C Paul, H Li, M Liu… - Genes, 2020 - mdpi.com
Background: We demonstrated that the transduction of Wnt11 into mesenchymal stem cells
(MSCs)(MSCWnt11) promotes these cells differentiation into cardiac phenotypes. In the …
(MSCs)(MSCWnt11) promotes these cells differentiation into cardiac phenotypes. In the …
C1q/TNF‐related protein 4 mediates proliferation and migration of vascular smooth muscle cells during vascular remodelling
J Liu, X Long, H Li, Q Yan, L Wang… - Clinical and …, 2023 - Wiley Online Library
Background Vascular remodelling is an essential pathophysiological state in many
circulatory diseases. Abnormal vascular smooth muscle cell (VSMC) behaviour leads to …
circulatory diseases. Abnormal vascular smooth muscle cell (VSMC) behaviour leads to …
[HTML][HTML] Lnc-C2orf63-4-1 confers VSMC homeostasis and prevents aortic dissection formation via STAT3 interaction
S Zhang, S Zhao, X Han, Y Zhang, X Jin… - Frontiers in cell and …, 2021 - frontiersin.org
Emerging evidence indicates that long non-coding RNAs (lncRNAs) serve as a critical
molecular regulator in various cardiovascular diseases. Here, we aimed to identify and …
molecular regulator in various cardiovascular diseases. Here, we aimed to identify and …
[HTML][HTML] SLC44A2 regulates vascular smooth muscle cell phenotypic switching and aortic aneurysm
T Song, S Zhao, S Luo, C Chen, X Liu, X Wu… - The Journal of Clinical …, 2024 - jci.org
Aortic aneurysm is a life-threatening disease with limited interventions that is closely related
to vascular smooth muscle cell (VSMC) phenotypic switching. SLC44A2, a member of the …
to vascular smooth muscle cell (VSMC) phenotypic switching. SLC44A2, a member of the …
[HTML][HTML] Impaired LRP6-TCF7L2 activity enhances smooth muscle cell plasticity and causes coronary artery disease
R Srivastava, J Zhang, G Go, A Narayanan, TP Nottoli… - Cell reports, 2015 - cell.com
Mutations in Wnt-signaling coreceptor LRP6 have been linked to coronary artery disease
(CAD) by unknown mechanisms. Here, we show that reduced LRP6 activity in LRP6 R611C …
(CAD) by unknown mechanisms. Here, we show that reduced LRP6 activity in LRP6 R611C …
TGF-β/Smad3 promotes smooth muscle cell de-differentiation and proliferation through crosstalk with the Wnt/β-catenin pathway
M Chaudhary, D Direnzo, XD Shi, S Franco… - … and Vascular Biology, 2015 - Am Heart Assoc
Introduction: Endovascular interventions are the first line treatment for patients with
atherosclerotic disease. However, a significant number of these fail due to neointimal …
atherosclerotic disease. However, a significant number of these fail due to neointimal …
Loss of LRP6/TCF7L2 regulation of vascular smooth muscle cell phenotype contributes to coronary artery disease
R Srivastava, G Go, J Zhang, A Mani - Circulation, 2014 - Am Heart Assoc
Loss of function mutations in the Wnt co-receptor Low Density Lipoprotein Receptor Related
Protein 6 (LRP6) cause early coronary artery disease (CAD) in humans. Using in vivo model …
Protein 6 (LRP6) cause early coronary artery disease (CAD) in humans. Using in vivo model …
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- proliferation and migration muscle cells
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