The construction of C− C bonds with complete control of the stereochemical course of a
reaction is of utmost importance for organic synthesis. The aldol reaction—the simple …

Can a simple organic molecule act like an enzyme? If this were possible, it would represent
a remarkable synthetic alternative to many established asymmetric transformations. In …

The aldol reaction, in addition to being an effective method for the formation of CÀC bonds in
organic synthesis,[1] is also a critical biological reaction in the context of metabolism. The …

Asymmetric aldol reactions are a powerful method for the construction of carbon–carbon
bonds in an enantioselective fashion. Historically this reaction has been performed in a …

In the synthesis of complex molecular targets, the ability to control the stereoselectivity of the
aldol reaction has raised this process to a level of prominence shared by few reactions. In …

In 1935, RC Fuson formulated the principle of vinylogy to explain how the influence of a
functional group may be felt at a distant point in the molecule when this position is …

The aldol reaction is among the most important methods of forming carbon‐carbon bonds.
The addition of an enolate to an aldehyde leads to the formation of at least one chiral center …

The direct catalytic asymmetric aldol reaction is one of the most fundamental transformations
in organic synthesis, and several efficient asymmetric methodologies for this reaction using …

The asymmetric aldol reaction is one of the most powerful synthetic tools for carbon–carbon
bond-forming reactions. This method provides a beneficial route to access chiral β-hydroxy …

The aldol reaction is among the most powerful and strategically important carbon–carbon
bond–forming transformations in organic chemistry. The importance of the aldol reaction in …