Inhalable microparticles as drug delivery systems to the lungs in a dry powder formulations

K Knap, K Kwiecień… - Regenerative …, 2023 - academic.oup.com
Inhalation-administrated drugs remain an interesting possibility of addressing pulmonary
diseases. Direct drug delivery to the lungs allows one to obtain high concentration in the site …

[PDF][PDF] Recent advancements and applications of inhalable microparticles based drug delivery systems in respiratory disorders

N Kanojia, S Singh, J Singh, N Sharma… - … Res. Appl. Chem, 2021 - researchgate.net
Lower respiratory infections are the third leading cause of death, as stated by the world
health organization. The pulmonary route requires reduced dose, exhibits immediate drug …

Sustainable strategies for nano-in-micro particle engineering for pulmonary delivery

AS Silva, MT Tavares, A Aguiar-Ricardo - Journal of nanoparticle research, 2014 - Springer
With the increasing popularity and refinement of inhalation therapy, there has been a huge
demand for the design and development of fine-tuned inhalable drug particles capable of …

Inhalable nanocomposite microparticles: preparation, characterization and factors affecting formulation

I Elsayed, MHH AbouGhaly - Expert Opinion on Drug Delivery, 2016 - Taylor & Francis
Introduction: Nanocomposite microparticles are intelligent carriers utilised for pulmonary
drug delivery. These carriers are composed of drug-encapsulated nanoparticles dispersed …

Biodegradable nano-micro carrier systems for sustained pulmonary drug delivery:(I) self-assembled nanoparticles encapsulated in respirable/swellable semi-IPN …

IM El-Sherbiny, HDC Smyth - International journal of pharmaceutics, 2010 - Elsevier
Design of appropriate inhaled carriers with adequate aerodynamic properties, drug release,
biodegradation and evasion of macrophage uptake is a major challenge for controlled …

Recent advances in the development of microparticles for pulmonary administration

H Jain, A Bairagi, S Srivastava, SB Singh… - Drug discovery today, 2020 - Elsevier
Highlights•The pulmonary route is an efficient route for respiratory diseases.•Technosphere
® and PulmoSphere™ are novel inhalable technologies for drug delivery.•Microparticles are …

Dry powder form of polymeric nanoparticles for pulmonary drug delivery

F Shiehzadeh, M Tafaghodi - Current Pharmaceutical Design, 2016 - ingentaconnect.com
Delivery to the lungs is an efficient way to deliver drugs directly to the site of action or to the
blood circulation. Because of limitations of direct administration of free drugs, particulate …

Inhalation of sustained release microparticles for the targeted treatment of respiratory diseases

G Pulivendala, S Bale, C Godugu - Drug delivery and translational …, 2020 - Springer
Delivering drugs through inhalation for systemic and local applications has been in practice
since several decades to treat various diseases. In recent times, inhalation drug delivery is …

Delivery of dry powders to the lungs: Influence of particle attributes from a biological and technological point of view

S Zellnitz, E Roblegg, J Pinto… - Current Drug Delivery, 2019 - ingentaconnect.com
Dry powder inhalers are medical devices used to deliver powder formulations of active
pharmaceutical ingredients via oral inhalation to the lungs. Drug particles, from a biological …

Novel cryomilled physically cross-linked biodegradable hydrogel microparticles as carriers for inhalation therapy

IM El-Sherbiny, HDC Smyth - Journal of microencapsulation, 2010 - Taylor & Francis
In this study, novel biodegradable physically cross-linked hydrogel microparticles were
developed and evaluated in-vitro as potential carriers for inhalation therapy. These hydrogel …