NETopathic inflammation in chronic obstructive pulmonary disease and severe asthma
M Uddin, H Watz, A Malmgren, F Pedersen - Frontiers in immunology, 2019 - frontiersin.org
Neutrophils play a central role in innate immunity, inflammation, and resolution. Unresolving
neutrophilia features as a disrupted inflammatory process in the airways of patients with …
neutrophilia features as a disrupted inflammatory process in the airways of patients with …
Neutrophil extracellular traps in chronic lung disease: implications for pathogenesis and therapy
HR Keir, JD Chalmers - European Respiratory Review, 2022 - Eur Respiratory Soc
Neutrophilic inflammation has a key role in the pathophysiology of multiple chronic lung
diseases. The formation of neutrophil extracellular traps (NETs) has emerged as a key …
diseases. The formation of neutrophil extracellular traps (NETs) has emerged as a key …
Neutrophil extracellular traps in asthma: friends or foes?
Asthma is a chronic inflammatory disease characterized by variable airflow limitation and
airway hyperresponsiveness. A plethora of immune and structural cells are involved in …
airway hyperresponsiveness. A plethora of immune and structural cells are involved in …
Orchestration of neutrophil extracellular traps (Nets), a unique innate immune function during chronic obstructive pulmonary disease (COPD) development
A Trivedi, MA Khan, G Bade, A Talwar - Biomedicines, 2021 - mdpi.com
Morbidity, mortality and economic burden caused by chronic obstructive pulmonary disease
(COPD) is a significant global concern. Surprisingly, COPD is already the third leading …
(COPD) is a significant global concern. Surprisingly, COPD is already the third leading …
NET balancing: a problem in inflammatory lung diseases
OZ Cheng, N Palaniyar - Frontiers in immunology, 2013 - frontiersin.org
Neutrophil extracellular traps (NETs) are beneficial antimicrobial defense structures that can
help fight against invading pathogens in the host. However, recent studies reveal that NETs …
help fight against invading pathogens in the host. However, recent studies reveal that NETs …
Neutrophil extracellular traps in airway diseases: Pathological roles and therapeutic implications
A Jo, DW Kim - International Journal of Molecular Sciences, 2023 - mdpi.com
Neutrophils are important effector cells of the innate immune response that fight pathogens
by phagocytosis and degranulation. Neutrophil extracellular traps (NETs) are released into …
by phagocytosis and degranulation. Neutrophil extracellular traps (NETs) are released into …
A fragile balance: does neutrophil extracellular trap formation drive pulmonary disease progression?
H Block, A Zarbock - Cells, 2021 - mdpi.com
Neutrophils act as the first line of defense during infection and inflammation. Once activated,
they are able to fulfil numerous tasks to fight inflammatory insults while keeping a balanced …
they are able to fulfil numerous tasks to fight inflammatory insults while keeping a balanced …
Neutrophil extracellular traps in pulmonary diseases: too much of a good thing?
Neutrophil extracellular traps (NETs) arise from the release of granular and nuclear contents
of neutrophils in the extracellular space in response to different classes of microorganisms …
of neutrophils in the extracellular space in response to different classes of microorganisms …
The emerging role of neutrophil extracellular traps in respiratory disease
SH Twaddell, KJ Baines, C Grainge, PG Gibson - Chest, 2019 - Elsevier
Neutrophil extracellular traps (NETs) are extrusions of intracellular DNA and attached
granular material that enable bacterial killing. NETs are increasingly recognized for their role …
granular material that enable bacterial killing. NETs are increasingly recognized for their role …
Neutrophil extracellular traps in respiratory disease: guided anti-microbial traps or toxic webs?
B Cortjens, JBM van Woensel, RA Bem - Paediatric respiratory reviews, 2017 - Elsevier
Neutrophil recruitment to the airways and lungs is a major hallmark of many respiratory
diseases. One of the more recently discovered unique innate immune effector mechanisms …
diseases. One of the more recently discovered unique innate immune effector mechanisms …