Phosphatidic acid (PA) is the simplest cellular glycerophospholipid characterized by unique
biophysical properties: a small headgroup; negative charge; and a phosphomonoester …

Phosphatidic acid (PA) is the simplest glycerophospholipid naturally occurring in living
organisms, and even though its content among other cellular lipids is minor, it is drawing …

The formation of phosphatidic acid (PA) from lysophosphatidic acid (LPA), diacylglycerol, or
phosphatidylcholine plays a key role in the regulation of intracellular membrane fission …

Lipids function not only as the major structural components of cell membranes, but also as
molecular messengers that transduce signals to trigger downstream signaling events in the …

Phosphatidic acid is the simplest (diacyl) glycerophospholipid present in cells and is now a
well established second messenger with direct biological functions. It is specifically …

The local generation of phosphatidic acid plays a key role in the regulation of intracellular
membrane transport through mechanisms which are largely unknown. Phosphatidic acid …

Phosphatidic acid and lysophosphatidic acid are minor but important anionic bioactive lipids
involved in a number of key cellular processes, yet these molecules have a simple …

Under physiological conditions, phosphatidic acid (PA) is an anionic phospholipid with
moderate biological reactivity. Some of its biological effects can be attributed to lyso-PA and …

Among the cellular lipids, phosphatidic acid (PA) is a peculiar one as it is at the same time a
key building block of phospholipid synthesis and a major lipid second messenger conveying …

Phosphatidic acid (PA) is a crucial membrane phospholipid involved in de novo lipid
synthesis and numerous intracellular signaling cascades. The signaling function of PA is …