The first mutation in a gene associated with a neuronal migration disorder was identified in
patients with Kallmann Syndrome, characterized by hypogonadotropic hypogonadism and …

Gonadotropin-releasing hormone (GnRH) and olfactory neurons migrate together in
embryologic development, and disruption of this process causes idiopathic …

The development of Gonadotropin releasing hormone-1 (GnRH) neurons is important for a
functional reproduction system in vertebrates. Disruption of GnRH results in hypogonadism …

ABSTRACT Gonadotropin-releasing hormone-1 (GnRH-1) neurons (GnRH-1 ns) migrate
from the developing olfactory pit into the hypothalamus during embryonic development …

During the past 20 years, remarkable advances have been made regarding the molecular
basis of many disorders affecting reproduction. This is particularly true for patients who …

Context: Gonadotropin-releasing hormone neurons originate outside the central nervous
system in the olfactory placode and migrate into the central nervous system, becoming …

Infertility and inability to smell are the phenotypical features of Kallmann's syndrome (KS), a
genetic disease which affects 1 in 10,000 males and 1 in 50,000 females, the majority of the …

Gonadotropin Releasing Hormone (GnRH) is a key regulator of reproduction and sexual
behaviour. During the last decade, embryological studies have clarified the question of the …

Kallmann syndrome (KS) is a genetic disease characterized by hypogonadotropic
hypogonadism and impaired sense of smell. The genetic causes underlying this syndrome …

Gonadotropin releasing hormone (GnRH) neurons originate the nasal placode and migrate
into the brain during prenatal development. Once within the brain, these cells become …