[HTML][HTML] Technological and practical challenges of dry powder inhalers and formulations
M Hoppentocht, P Hagedoorn, HW Frijlink… - Advanced drug delivery …, 2014 - Elsevier
In the 50 years following the introduction of the first dry powder inhaler to the market, several
developments have occurred. Multiple-unit dose and multi-dose devices have been …
developments have occurred. Multiple-unit dose and multi-dose devices have been …
Powder production and particle engineering for dry powder inhaler formulations
Dry powder inhalers have become increasingly attractive for pulmonary delivery of locally
and systemically effective medications. In comparison to the liquid counterparts, such as …
and systemically effective medications. In comparison to the liquid counterparts, such as …
Dry powder inhalers: an overview
PJ Atkins - Respiratory care, 2005 - rc.rcjournal.com
Dry powder inhalers (DPIs) are a widely accepted inhaled delivery dosage form, particularly
in Europe, where they currently are used by a large number of patients for the delivery of …
in Europe, where they currently are used by a large number of patients for the delivery of …
Evolution of dry powder inhaler design, formulation, and performance
SP Newman, WW Busse - Respiratory medicine, 2002 - Elsevier
Many companies are now prioritizing the development of dry powder inhalers (DPIs) above
pressurized formulations of asthma drugs. A well-designed DPI and an appropriate powder …
pressurized formulations of asthma drugs. A well-designed DPI and an appropriate powder …
Dry powder inhaler formulation
MJ Telko, AJ Hickey - Respiratory care, 2005 - rc.rcjournal.com
A drug product combines pharmacologic activity with pharmaceutical properties. Desirable
performance characteristics are physical and chemical stability, ease of processing …
performance characteristics are physical and chemical stability, ease of processing …
Developing an efficient and reliable dry powder inhaler for pulmonary drug delivery–a review for multidisciplinary researchers
Pulmonary drug delivery is the focus of much research and development because of its
great potential to produce maximum therapeutic benefit. Among the available options the dry …
great potential to produce maximum therapeutic benefit. Among the available options the dry …
Dry powder inhalers for pulmonary drug delivery
HW Frijlink, AH De Boer - Expert opinion on drug delivery, 2004 - Taylor & Francis
The pulmonary route is an interesting route for drug administration, both for effective local
therapy (asthma, chronic obstructive pulmonary disease or cystic fibrosis) and for the …
therapy (asthma, chronic obstructive pulmonary disease or cystic fibrosis) and for the …
Dry powder formulations for pulmonary delivery
RJ Malcolmson, JK Embleton - Pharmaceutical Science & Technology …, 1998 - Elsevier
This review examines the key issues surrounding the development and preparation of
formulations for dry powder inhalers. The various inhaler devices that are currently available …
formulations for dry powder inhalers. The various inhaler devices that are currently available …
Review of dry powder inhalers
D Prime, PJ Atkins, A Slater, B Sumby - Advanced drug delivery reviews, 1997 - Elsevier
The search for alternatives to metered-dose inhalers has accelerated recently in a bid to find
effective products that do not use chlorofluorocarbon (CFC) propellants. This paper reviews …
effective products that do not use chlorofluorocarbon (CFC) propellants. This paper reviews …
Developing and advancing dry powder inhalation towards enhanced therapeutics
S Stegemann, S Kopp, G Borchard, VP Shah… - European journal of …, 2013 - Elsevier
Enhanced therapeutics are drug products derived from existing generic drugs that provide
additional benefits to the patients and the healthcare system. Enhanced therapeutics are …
additional benefits to the patients and the healthcare system. Enhanced therapeutics are …