[HTML][HTML] Technological and practical challenges of dry powder inhalers and formulations

M Hoppentocht, P Hagedoorn, HW Frijlink… - Advanced drug delivery …, 2014 - Elsevier
In the 50 years following the introduction of the first dry powder inhaler to the market, several
developments have occurred. Multiple-unit dose and multi-dose devices have been …

Powder production and particle engineering for dry powder inhaler formulations

YW Lin, J Wong, L Qu, HK Chan… - Current pharmaceutical …, 2015 - ingentaconnect.com
Dry powder inhalers have become increasingly attractive for pulmonary delivery of locally
and systemically effective medications. In comparison to the liquid counterparts, such as …

Dry powder inhalers: an overview

PJ Atkins - Respiratory care, 2005 - rc.rcjournal.com
Dry powder inhalers (DPIs) are a widely accepted inhaled delivery dosage form, particularly
in Europe, where they currently are used by a large number of patients for the delivery of …

Evolution of dry powder inhaler design, formulation, and performance

SP Newman, WW Busse - Respiratory medicine, 2002 - Elsevier
Many companies are now prioritizing the development of dry powder inhalers (DPIs) above
pressurized formulations of asthma drugs. A well-designed DPI and an appropriate powder …

Dry powder inhaler formulation

MJ Telko, AJ Hickey - Respiratory care, 2005 - rc.rcjournal.com
A drug product combines pharmacologic activity with pharmaceutical properties. Desirable
performance characteristics are physical and chemical stability, ease of processing …

Developing an efficient and reliable dry powder inhaler for pulmonary drug delivery–a review for multidisciplinary researchers

N Islam, MJ Cleary - Medical engineering & physics, 2012 - Elsevier
Pulmonary drug delivery is the focus of much research and development because of its
great potential to produce maximum therapeutic benefit. Among the available options the dry …

Dry powder inhalers for pulmonary drug delivery

HW Frijlink, AH De Boer - Expert opinion on drug delivery, 2004 - Taylor & Francis
The pulmonary route is an interesting route for drug administration, both for effective local
therapy (asthma, chronic obstructive pulmonary disease or cystic fibrosis) and for the …

Dry powder formulations for pulmonary delivery

RJ Malcolmson, JK Embleton - Pharmaceutical Science & Technology …, 1998 - Elsevier
This review examines the key issues surrounding the development and preparation of
formulations for dry powder inhalers. The various inhaler devices that are currently available …

Review of dry powder inhalers

D Prime, PJ Atkins, A Slater, B Sumby - Advanced drug delivery reviews, 1997 - Elsevier
The search for alternatives to metered-dose inhalers has accelerated recently in a bid to find
effective products that do not use chlorofluorocarbon (CFC) propellants. This paper reviews …

Developing and advancing dry powder inhalation towards enhanced therapeutics

S Stegemann, S Kopp, G Borchard, VP Shah… - European journal of …, 2013 - Elsevier
Enhanced therapeutics are drug products derived from existing generic drugs that provide
additional benefits to the patients and the healthcare system. Enhanced therapeutics are …