As highly reduced hydrocarbons are abundant in the environment, enzymes that catalyze
the terminal or subterminal oxygenation of alkanes are relatively easy to find. A number of …

Oxidoreductases catalyze a large variety of regio-, stereo-, and chemoselective hydrocarbon
oxyfunctionalizations, reactions, which are important in industrial organic synthesis but …

Environmental microbes utilize four degradation pathways for the oxidation of n-alkanes.
Although the enzymes degrading n-alkanes in different microbes may vary, enzymes …

The oxidation of alkanes into valuable chemical products is a vital reaction in organic
synthesis. This reaction, however, is challenging, owing to the inertness of C− H bonds …

The first step in the aerobic degradation of alkanes by bacteria, yeasts, and fungi is
catalyzed by oxygenases. These enzymes, which introduce oxygen atoms derived from …

Long-chain alkane waxes are synthesized by a wide variety of organisms, including plants,
animals, and microorganisms. 1− 4 Although chemically alkanes are among the most boring …

The evolutionary pressures that shaped the specificity and catalytic efficiency of enzymes
can only be speculated. While directed evolution experiments show that new functions can …

Biologically produced alkanes represent potential renewable alternatives to petroleum-
derived chemicals. A cyanobacterial pathway consisting of acyl–Acyl Carrier Protein …

We have converted cytochrome P450 BM-3 from Bacillus megaterium (P450 BM-3), a
medium-chain (C12–C18) fatty acid monooxygenase, into a highly efficient catalyst for the …

Oxygenases carry out the regio-, stereo-and chemoselective introduction of oxygen in a
tremendous range of organic molecules. This versatility has already been exploited in …