Scratching the surface of the protein corona: Challenging measurements and controversies
This Review aims to provide a systematic analysis of the literature regarding ongoing
debates in protein corona research. Our goal is to portray the current understanding of two …
debates in protein corona research. Our goal is to portray the current understanding of two …
Protein corona formation around nanoparticles–from the past to the future
The protein adsorption layer (aka the “protein corona”) that forms on the surface of colloidal
nanoparticles plays an important role in their interaction with living matter. Thus …
nanoparticles plays an important role in their interaction with living matter. Thus …
Mechanistic understanding of protein Corona formation around nanoparticles: old puzzles and new insights
K Nienhaus, GU Nienhaus - Small, 2023 - Wiley Online Library
Although a wide variety of nanoparticles (NPs) have been engineered for use as disease
markers or drug delivery agents, the number of nanomedicines in clinical use has hitherto …
markers or drug delivery agents, the number of nanomedicines in clinical use has hitherto …
[HTML][HTML] Protein corona–from molecular adsorption to physiological complexity
L Treuel, D Docter, M Maskos… - Beilstein journal of …, 2015 - beilstein-journals.org
In biological environments, nanoparticles are enshrouded by a layer of biomolecules,
predominantly proteins, mediating its subsequent interactions with cells. Detecting this …
predominantly proteins, mediating its subsequent interactions with cells. Detecting this …
A decade of the protein corona
In this Perspective, we reflect on a decade of research on the protein corona and
contemplate its broad implications for future science and engineering at the bio–nano …
contemplate its broad implications for future science and engineering at the bio–nano …
Possibilities and limitations of different separation techniques for the analysis of the protein corona
C Weber, S Morsbach… - Angewandte Chemie …, 2019 - Wiley Online Library
One of the biggest challenges in the field of nanomedicine is the adsorption of biomolecules
on the nanomaterial upon contact with a biological medium. The interactions of the resulting …
on the nanomaterial upon contact with a biological medium. The interactions of the resulting …
Protein corona formation for nanomaterials and proteins of a similar size: hard or soft corona?
Nanoparticles (NPs) entering a biological fluid undergo surface modification due to dynamic,
physicochemical interactions with biological components, especially proteins. In this work …
physicochemical interactions with biological components, especially proteins. In this work …
[HTML][HTML] Hard and soft protein corona of nanomaterials: Analysis and relevance
R García-Álvarez, M Vallet-Regí - Nanomaterials, 2021 - mdpi.com
Upon contact with a biological milieu, nanomaterials tend to interact with biomolecules
present in the media, especially proteins, leading to the formation of the so-called “protein …
present in the media, especially proteins, leading to the formation of the so-called “protein …
Exploiting the novel properties of protein coronas: emerging applications in nanomedicine
K Hamad-Schifferli - Nanomedicine, 2015 - Future Medicine
Protein coronas have been the focus of a great deal of study recently due to their inevitable
formation and their impact on the biological consequences of nanomaterials. Although the …
formation and their impact on the biological consequences of nanomaterials. Although the …
The protein corona on nanoparticles as viewed from a nanoparticle‐sizing perspective
Most surfaces of engineered nanoparticles (NPs) are reactive toward biomolecules.
Therefore, whenever NPs become immersed in biological fluids, proteins and other …
Therefore, whenever NPs become immersed in biological fluids, proteins and other …