Advances in the Study of Etiology and Molecular Mechanisms of Sensorineural Hearing Loss

C He, H Gai, W Zhao, H Zhang, L Lai, C Ding… - Cell Biochemistry and …, 2024 - Springer
Sensorineural hearing loss (SNHL), a multifactorial progressive disorder, results from a
complex interplay of genetic and environmental factors, with its underlying mechanisms …

[HTML][HTML] Molecular mechanisms of sensorineural hearing loss and hearing protection

SM Vlajkovic, AC Vélez-Ortega… - Frontiers in Molecular …, 2024 - frontiersin.org
More than 1.5 billion people experience declining hearing ability during their lifetime. With
an aging population and increased exposure to excessive noise, there has never been a …

[HTML][HTML] Hearing loss in neurological disorders

S Li, C Cheng, L Lu, X Ma, X Zhang, A Li… - Frontiers in cell and …, 2021 - frontiersin.org
Sensorineural hearing loss (SNHL) affects approximately 466 million people worldwide,
which is projected to reach 900 million by 2050. Its histological characteristics are lesions in …

Advancements in prevention and intervention of sensorineural hearing loss

H Ren, B Hu, G Jiang - Therapeutic advances in chronic …, 2022 - journals.sagepub.com
The inner ear is a complex and difficult organ to study, and sensorineural hearing loss
(SNHL) is a multifactorial sensorineural disorder with characteristics of impaired speech …

Role of mitochondrial dysfunction and oxidative stress in sensorineural hearing loss

WJT Tan, L Song - Hearing research, 2023 - Elsevier
Sensorineural hearing loss (SNHL) can either be genetically inherited or acquired as a
result of aging, noise exposure, or ototoxic drugs. Although the precise pathophysiological …

[HTML][HTML] Hearing loss and brain disorders: A review of multiple pathologies

OG Oluwole, K James, A Yalcouye, A Wonkam - Open Medicine, 2021 - degruyter.com
Several causative factors are associated with hearing loss (HL) and brain disorders.
However, there are many unidentified disease modifiers in these conditions. Our study …

[HTML][HTML] Molecular mechanisms of sensorineural hearing loss and development of inner ear therapeutics

SM Vlajkovic, PR Thorne - International Journal of Molecular Sciences, 2021 - mdpi.com
The sense of hearing enables us to enjoy sounds and music and engage with other people.
The sense of hearing is, however, vulnerable to environmental challenges, such as …

[HTML][HTML] Integrative functional transcriptomic analyses implicate shared molecular circuits in sensorineural hearing loss

P Chen, JJ Hao, MW Li, J Bai, YT Guo… - Frontiers in Cellular …, 2022 - frontiersin.org
Sensorineural hearing loss (SNHL) is referred to as the most common type of hearing loss
and typically occurs when the inner ear or the auditory nerve is damaged. Aging, noise …

[HTML][HTML] Aging, neurogenesis and neuroinflammation in hearing loss and protection

M Magariños, M Milo, I Varela-Nieto - Frontiers in aging neuroscience, 2015 - frontiersin.org
Hearing loss affects 360 million people worldwide and it is estimated that this number will
exceed 900 million by 2025 (World Health Organization. Fact sheet N◦ 300, March 2015) …

[HTML][HTML] New insights in molecular pathways in ototoxicity

Q Yang, C Chen, J Li - Frontiers in Cellular Neuroscience, 2023 - frontiersin.org
Ototoxicity refers to damage to the inner ear, characterized by cochlear (cochleotoxicity) or
vestibular (vestibulotoxicity) dysfunction (Steyger et al., 2018). Auditory dysfunction is one of …