The present invention provides therapeutic compound for prevention and treatment of
primary biliary cholangitis,(PBC). Specifically, the present invention provides pharma …

The present invention provides therapeutic compound for prevention and treatment of
primary biliary cholangitis,(PBC). Specifically, the present invention provides pharma …

2. Background Information Cholestasis is a pathological condition where the choleresis,
which is one of the important functions of the liver, is suppressed and the bile flow from the …

The present invention relates to, inter alia, methods of treatment and combinations of (R)-2-
(7-(4-cyclopentyl-3 (tri-fluoromethyl) benzyloxy)-1, 2, 3, 4-tetrahydrocyclopenta [b] indol-3-yl) …

US10676500B2 - Process for preparation of sulfonyl carbamate bile acid derivatives - Google
Patents US10676500B2 - Process for preparation of sulfonyl carbamate bile acid derivatives …

US10584145B2 - Process for preparation of sulfonylurea bile acid derivatives - Google
Patents US10584145B2 - Process for preparation of sulfonylurea bile acid derivatives …

US10414774B2 - Compound useful for altering the levels of bile acids for the treatment of
diabetes and cardiometabolc disease - Google Patents US10414774B2 - Compound useful for …

US5321019A - Bile acid sulfurated derivatives - Google Patents US5321019A - Bile acid
sulfurated derivatives - Google Patents Bile acid sulfurated derivatives Download PDF Info …

The compounds of general formula (I) are important COOH intermediates for the preparation
of compounds useful for a number of pharmaceutical applications. They are, for example …

The present inventors further studied bile acid reabsorption inhibitors to Search for agents
that decrease the cholesterol level, and found that Such inhibitors exhibit the preventive and …