The ribosome is a multi-unit complex that translates mRNA into protein. Ribosome
biogenesis is the process that generates ribosomes and plays an essential role in cell …

The ability to translate genetic information into functional proteins is considered a landmark
in evolution. Ribosomes have evolved to take on this responsibility and, although there are …

Ribosome biogenesis is critical for cells to generate the ribosomes they need for protein
synthesis in order to survive, grow and proliferate. It is a complex process, involving the …

Signaling through the mammalian target of rapamycin, complex 1 (mTORC1), positively
regulates the transcription of ribosomal RNA (rRNA) and the synthesis of ribosomal proteins …

Ribosomes are nanomachines essential for protein production in all living cells. Ribosome
synthesis increases in cancer cells to cope with a rise in protein synthesis and sustain …

The target of rapamycin (TOR) signal-transduction pathway is an important mechanism by
which eucaryotic cells adjust their protein biosynthetic capacity to nutrient availability. Both …

Ribosomes are a complex ensemble of rRNA and ribosomal proteins that function as mRNA
translation machines. Ribosome biogenesis is a multistep process that begins in the …

Ribosome biogenesis and protein synthesis are fundamental rate-limiting steps for cell
growth and proliferation. The ribosomal proteins (RPs), comprising the structural parts of the …

mTORC1 (mammalian target of rapamycin complex 1) is controlled by diverse signals (eg
hormones, growth factors, nutrients and cellular energy status) and regulates a range of …

The biosynthesis of ribosomes is a complex process that requires the coordinated action of
many factors and a huge energy investment from the cell. Ribosomes are essential for …