Delivery of bone morphogenetic protein-2 and substance P using graphene oxide for bone regeneration
In this study, we demonstrate that graphene oxide (GO) can be used for the delivery of bone
morphogenetic protein-2 (BMP-2) and substance P (SP), and that this delivery promotes …
morphogenetic protein-2 (BMP-2) and substance P (SP), and that this delivery promotes …
Enhancing cell proliferation and osteogenic differentiation of MC3T3-E1 pre-osteoblasts by BMP-2 delivery in graphene oxide-incorporated PLGA/HA biodegradable …
C Fu, X Yang, S Tan, L Song - Scientific reports, 2017 - nature.com
Lack of bioactivity has seriously restricted the development of biodegradable implants for
bone tissue engineering. Therefore, surface modification of the composite is crucial to …
bone tissue engineering. Therefore, surface modification of the composite is crucial to …
Bone morphogenetic protein-2 for bone regeneration–Dose reduction through graphene oxide-based delivery
High doses of bone morphogenetic protein-2 (BMP-2) are required for effective bone
regeneration. However, these high doses often cause undesirable adverse effects, including …
regeneration. However, these high doses often cause undesirable adverse effects, including …
Delivery of a therapeutic protein for bone regeneration from a substrate coated with graphene oxide
The therapeutic efficacy of drugs often depends on the drug delivery carrier. For efficient
delivery of therapeutic proteins, delivery carriers should enable the loading of large doses …
delivery of therapeutic proteins, delivery carriers should enable the loading of large doses …
Graphene oxide scaffold accelerates cellular proliferative response and alveolar bone healing of tooth extraction socket
E Nishida, H Miyaji, A Kato, H Takita… - International journal …, 2016 - Taylor & Francis
Graphene oxide (GO) consisting of a carbon monolayer has been widely investigated for
tissue engineering platforms because of its unique properties. For this study, we fabricated a …
tissue engineering platforms because of its unique properties. For this study, we fabricated a …
Graphene nanoparticles as osteoinductive and osteoconductive platform for stem cell and bone regeneration
H Elkhenany, S Bourdo, S Hecht, R Donnell… - … , Biology and Medicine, 2017 - Elsevier
The potential of graphene-based nanoparticles (GNPs) has recently gained significant
attention in biomedicine, especially in tissue engineering. In this study, we investigated the …
attention in biomedicine, especially in tissue engineering. In this study, we investigated the …
[HTML][HTML] Biocompatible reduced graphene oxide stimulated BMSCs induce acceleration of bone remodeling and orthodontic tooth movement through promotion on …
D Jiao, J Wang, W Yu, K Zhang, N Zhang, L Cao… - Bioactive Materials, 2022 - Elsevier
We has synthesized the biocompatible gelatin reduced graphene oxide (GOG) in previous
research, and in this study we would further evaluate its effects on bone remodeling in the …
research, and in this study we would further evaluate its effects on bone remodeling in the …
Enhanced osteogenesis by reduced graphene oxide/hydroxyapatite nanocomposites
JH Lee, YC Shin, SM Lee, OS Jin, SH Kang… - Scientific reports, 2015 - nature.com
Recently, graphene-based nanomaterials, in the form of two dimensional substrates or three
dimensional foams, have attracted considerable attention as bioactive scaffolds to promote …
dimensional foams, have attracted considerable attention as bioactive scaffolds to promote …
Graphene oxide‐copper Nanocomposite‐coated porous CaP scaffold for vascularized bone regeneration via activation of Hif‐1α
W Zhang, Q Chang, L Xu, G Li, G Yang… - Advanced …, 2016 - Wiley Online Library
Graphene has been studied for its in vitro osteoinductive capacity. However, the in vivo bone
repair effects of graphene‐based scaffolds remain unknown. The aqueous soluble …
repair effects of graphene‐based scaffolds remain unknown. The aqueous soluble …
Stimulated osteogenic differentiation of human mesenchymal stem cells by reduced graphene oxide
L Jin, JH Lee, OS Jin, YC Shin, MJ Kim… - … of nanoscience and …, 2015 - ingentaconnect.com
Osteoprogenitor cells play a significant role in the growth or repair of bones, and have great
potential as cell sources for regenerative medicine and bone tissue engineering, but control …
potential as cell sources for regenerative medicine and bone tissue engineering, but control …
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