Abstract Non-Alcoholic Fatty Liver Disease (NAFLD) comprises a wide spectrum of liver
injuries from simple steatosis to steatohepatitis and cirrhosis. Non-Alcoholic Steatohepatitis …

Non-alcoholic fatty liver disease (NAFLD) is a global health burden closely linked to insulin
resistance, obesity, and type 2 diabetes. The complex pathophysiology of NAFLD involves …

Background As a result of a sedentary lifestyle and excess food consumption in modern
society, non-alcoholic fatty liver disease (NAFLD) characterized by fat accumulation in the …

Nonalcoholic fatty liver disease (NAFLD) is primarily caused by abnormal lipid metabolism
and the accumulation of triglycerides in the liver. NAFLD is also associated with hepatic …

Nonalcoholic fatty liver disease (NAFLD) is a consequence of insulin resistance
encompassing a spectrum that extends from simple hepatic steatosis through to …

Nuclear receptors (NRs) are ligand-activated transcriptional regulators of several key
metabolic processes including hepatic lipid and glucose metabolism, bile acid homeostasis …

Nuclear receptors are transcription factors which sense changing environmental or
hormonal signals and effect transcriptional changes to regulate core life functions including …

Simple Summary In the context of liver disease, one of the more growing public health
problems is the transition from simple steatosis to non-alcoholic steatohepatitis. Profound …

Obesity and type 2 diabetes mellitus (T2DM) are metabolic disorders characterized by
metabolic inflexibility with multiple pathological organ manifestations, including non …

Members of the nuclear receptor (NR) superfamily of ligand‐activated transcription factors
are players of substantial relevance in the regulation of hepatic gene expression. NRs direct …