X-ray-activated nanosystems for theranostic applications

X Chen, J Song, X Chen, H Yang - Chemical Society Reviews, 2019 - pubs.rsc.org
X-rays are widely applied in clinical medical facilities for radiotherapy (RT) and biomedical
imaging. However, the sole use of X-rays for cancer treatment leads to insufficient radiation …

Breaking the depth dependence by nanotechnology‐enhanced X‐ray‐excited deep cancer theranostics

W Fan, W Tang, J Lau, Z Shen, J Xie, J Shi… - Advanced …, 2019 - Wiley Online Library
The advancements in nanotechnology have created multifunctional nanomaterials aimed at
enhancing diagnostic accuracy and treatment efficacy for cancer. However, the ability to …

Emerging nanotechnology and advanced materials for cancer radiation therapy

G Song, L Cheng, Y Chao, K Yang, Z Liu - Advanced materials, 2017 - Wiley Online Library
Radiation therapy (RT) including external beam radiotherapy (EBRT) and internal
radioisotope therapy (RIT) has been widely used for clinical cancer treatment. However …

High energy X-ray radiation sensitive scintillating materials for medical imaging, cancer diagnosis and therapy

L Lu, M Sun, Q Lu, T Wu, B Huang - Nano Energy, 2021 - Elsevier
X-rays are widely adopted in cancer radiotherapy and clinical diagnosis devices for
photodynamic therapy (PDT) and medical radiography. The sole utilization of X-ray …

[HTML][HTML] Development of nanotechnology-mediated precision radiotherapy for anti-metastasis and radioprotection

Y Pan, W Tang, W Fan, J Zhang, X Chen - Chemical Society Reviews, 2022 - pubs.rsc.org
Radiotherapy (RT), including external beam RT and internal radiation therapy, uses high-
energy ionizing radiation to kill tumor cells. However, ionizing radiation inevitably damages …

Advancing X-ray luminescence for imaging, biosensing, and theragnostics

Z Hong, Z Chen, Q Chen, H Yang - Accounts of Chemical …, 2022 - ACS Publications
Conspectus X-ray luminescence is an optical phenomenon in which chemical compounds
known as scintillators can emit short-wavelength light upon the excitation of X-ray photons …

Mechanisms for tuning engineered nanomaterials to enhance radiation therapy of cancer

S Clement, JM Campbell, W Deng, A Guller… - Advanced …, 2020 - Wiley Online Library
Engineered nanomaterials that produce reactive oxygen species on exposure to X‐and
gamma‐rays used in radiation therapy offer promise of novel cancer treatment strategies …

Tailoring radiotherapies and nanotechnology for targeted treatment of solid tumors

MI Khan, F Batool, R Ali, W Wang, S Li, G Wang… - Coordination Chemistry …, 2022 - Elsevier
Existing anticancer therapeutic modalities in clinical settings lack efficacy and fail to
completely cure cancers. Clearly understandable and mechanistic approaches are …

[HTML][HTML] Prospects of nanoparticle-based radioenhancement for radiotherapy

LRH Gerken, ME Gerdes, M Pruschy… - Materials horizons, 2023 - pubs.rsc.org
Radiotherapy is a key pillar of solid cancer treatment. Despite high level of conformal dose
deposition, radiotherapy is limited due to co-irradiation of organs-at risk and subsequent …

Progress in the development of nanosensitizers for X-ray-induced photodynamic therapy

XD Ren, XY Hao, HC Li, MR Ke, BY Zheng… - Drug Discovery …, 2018 - Elsevier
Highlights•X-ray-induced photodynamic (X-PDT) is a new approach to tackle deep tumors.•X-
ray-induced sensitizers (XSs) are the key to X-PDT.•The development of XSs is discussed in …