X-rays are widely applied in clinical medical facilities for radiotherapy (RT) and biomedical
imaging. However, the sole use of X-rays for cancer treatment leads to insufficient radiation …

X-rays are widely adopted in cancer radiotherapy and clinical diagnosis devices for
photodynamic therapy (PDT) and medical radiography. The sole utilization of X-ray …

Radiation therapy (RT) including external beam radiotherapy (EBRT) and internal
radioisotope therapy (RIT) has been widely used for clinical cancer treatment. However …

The advancements in nanotechnology have created multifunctional nanomaterials aimed at
enhancing diagnostic accuracy and treatment efficacy for cancer. However, the ability to …

Radiotherapy (RT), including external beam RT and internal radiation therapy, uses high-
energy ionizing radiation to kill tumor cells. However, ionizing radiation inevitably damages …

Conspectus X-ray luminescence is an optical phenomenon in which chemical compounds
known as scintillators can emit short-wavelength light upon the excitation of X-ray photons …

Engineered nanomaterials that produce reactive oxygen species on exposure to X‐and
gamma‐rays used in radiation therapy offer promise of novel cancer treatment strategies …

Existing anticancer therapeutic modalities in clinical settings lack efficacy and fail to
completely cure cancers. Clearly understandable and mechanistic approaches are …

Radiotherapy is a key pillar of solid cancer treatment. Despite high level of conformal dose
deposition, radiotherapy is limited due to co-irradiation of organs-at risk and subsequent …

Highlights•X-ray-induced photodynamic (X-PDT) is a new approach to tackle deep tumors.•X-
ray-induced sensitizers (XSs) are the key to X-PDT.•The development of XSs is discussed in …