Application of armodafinil-loaded microneedle patches against the negative influence induced by sleep deprivation

L Zhu, S Zhang, X Yu, S Zhu, G Ou, Q Li… - European Journal of …, 2021 - Elsevier
Cognition maintenance is essential for healthy and safe life if sleep deprivation happens.
Armodafinil is a wake-promoting agent against sleep deprivation related disorders …

Effects of armodafinil nanocrystal nasal hydrogel on recovery of cognitive function in sleep-deprived rats

S Zhu, S Zhang, L Pang, G Ou, L Zhu, J Ma, R Li… - International Journal of …, 2021 - Elsevier
Armodafinil is typically used in clinical practice to maintain cognition and wakefulness in
patients suffering from sleep deprivation. However, its poor water solubility and large …

CCD based development and characterization of nano-transethosome to augment the antidepressant effect of agomelatine on Swiss albino mice

MD Ansari, S Ahmed, SS Imam, I Khan… - Journal of Drug Delivery …, 2019 - Elsevier
This study was intended to develop and optimize agomelatine loaded lipid-based
transdermal vesicles (AGLTVs) for the treatment of depression. For the optimization purpose …

Quantitative determination of armodafinil in human plasma by liquid chromatography–electrospray mass spectrometry: Application to a clinical study

H Chandasana, J Kast, JA Bittman… - Biomedical …, 2018 - Wiley Online Library
Armodafinil is a wake‐promoting agent approved in 2007 by the US Food and Drug
Administration for the treatment of excessive sleepiness. A rapid, sensitive and selective …

Pharmacodynamic effects on alertness of single doses of armodafinil in healthy subjects during a nocturnal period of acute sleep loss

DF Dinges, S Arora, M Darwish… - Current medical research …, 2006 - Taylor & Francis
Objective: To assess the pharmacodynamics of armodafinil compared with modafinil and
placebo on measures of alertness in healthy volunteers undergoing sleep loss. Research …

Safety and efficacy of armodafinil in the treatment of excessive sleepiness

JN Brown, DT Wilson - Clinical Medicine Insights …, 2011 - journals.sagepub.com
Objective To review the efficacy and safety of armodafinil for the treatment in patients with
excessive sleepiness. Data sources Literature was accessed via MEDLINE (1966–February …

Armodafinil: a new treatment for excessive sleepiness

DA Lankford - Expert opinion on investigational drugs, 2008 - Taylor & Francis
Background: Armodafinil is a wake-promoting agent developed by Cephalon that was
approved in mid-2007 for the treatment of excessive sleepiness associated with narcolepsy …

Armodafinil in the treatment of sleep/wake disorders

JRL Schwartz, T Roth, C Drake - Neuropsychiatric disease and …, 2010 - Taylor & Francis
Excessive sleepiness (ES) is a major but underestimated public health concern associated
with significant impairments in alertness/wakefulness and significant morbidity. The term ES …

[HTML][HTML] Formulation and Characterization of Lacosamide-loaded Polymeric Microneedles

K Aykaç, E Başaran - Journal of Exploratory Research in …, 2022 - xiahepublishing.com
Methods In this study, Lacosamide was selected because of its high therapeutic dose, which
is due to its low transition to the target site. Microneedle patches were formulated by …

Armodafinil as a Potential Pharmacological Treatment for Attention Deficit Hyperactivity Disorder in Adults: A Review

R Lamas-Aguilar, A Diaz-Ruiz… - Current …, 2024 - ingentaconnect.com
Introduction: Armodafinil is a psychostimulant that promotes alertness, and it has been
shown to improve attention, memory, and fatigue in healthy adults and adults with …