Pharmacotherapy of type 2 diabetes: An update and future directions

A DeMarsilis, N Reddy, C Boutari, A Filippaios… - Metabolism, 2022 - Elsevier
Abstract Type 2 diabetes (T2D) is a widely prevalent disease with substantial economic and
social impact for which multiple conventional and novel pharmacotherapies are currently …

Pharmacotherapy of type 2 diabetes: an update

J Upadhyay, SA Polyzos, N Perakakis, B Thakkar… - Metabolism, 2018 - Elsevier
Abstract Type 2 diabetes (T2DM) is a leading cause of morbidity and mortality worldwide
and a major economic burden. The prevalence of T2DM is rising, suggesting more effective …

Therapeutics for type-2 diabetes mellitus: a glance at the recent inclusions and novel agents under development for use in clinical practice

N Shah, MA Abdalla, H Deshmukh… - Therapeutic …, 2021 - journals.sagepub.com
Diabetes mellitus (DM) is a chronic, progressive, and multifaceted illness resulting in
significant physical and psychological detriment to patients. As of 2019, 463 million people …

Novel therapies with precision mechanisms for type 2 diabetes mellitus

L Perreault, JS Skyler, J Rosenstock - Nature Reviews Endocrinology, 2021 - nature.com
Type 2 diabetes mellitus (T2DM) is one of the greatest health crises of our time and its
prevalence is projected to increase by> 50% globally by 2045. Currently, 10 classes of …

Pharmacology and therapeutic implications of current drugs for type 2 diabetes mellitus

AA Tahrani, AH Barnett, CJ Bailey - Nature Reviews Endocrinology, 2016 - nature.com
Type 2 diabetes mellitus (T2DM) is a global epidemic that poses a major challenge to health-
care systems. Improving metabolic control to approach normal glycaemia (where practical) …

Overview of clinically approved oral antidiabetic agents for the treatment of type 2 diabetes mellitus

ZX He, ZW Zhou, Y Yang, T Yang… - Clinical and …, 2015 - Wiley Online Library
Type 2 diabetes mellitus (T2 DM) is caused by insulin resistance and characterized by
progressive pancreatic β‐cell dysfunction. This articles reviews the application and …

Treating type 2 diabetes: how safe are current therapeutic agents?

J Philippe, D Raccah - International Journal of Clinical Practice, 2009 - Wiley Online Library
Sulphonylureas (SUs) and biguanides (metformin) are the current mainstays in the treatment
of type 2 diabetes (T2DM) and represent the most commonly used oral hypoglycaemic …

[HTML][HTML] New and emerging drugs and targets for type 2 diabetes: reviewing the evidence

BR Miller, H Nguyen, CJH Hu, C Lin… - American health & drug …, 2014 - ncbi.nlm.nih.gov
BACKGROUND Diabetes is a deadly and costly disease. The number of adults in the United
States with newly diagnosed diabetes has nearly tripled from 1980 to 2011. At the current …

Clinical review of antidiabetic drugs: implications for type 2 diabetes mellitus management

A Chaudhury, C Duvoor, VS Reddy Dendi… - Frontiers in …, 2017 - frontiersin.org
Type 2 diabetes mellitus (T2DM) is a global pandemic, as evident from the global
cartographic picture of diabetes by the International Diabetes Federation (http://www …

[HTML][HTML] Update on the treatment of type 2 diabetes mellitus

JJ Marín-Peñalver, I Martín-Timón… - World journal of …, 2016 - ncbi.nlm.nih.gov
To achieve good metabolic control in diabetes and keep long term, a combination of
changes in lifestyle and pharmacological treatment is necessary. Achieving near-normal …