High-grade serous ovarian cancer (HGSOC) is notoriously known as the “silent killer” of post-
menopausal women as it has an insidious progression and is the deadliest gynaecological …

Cancer–stroma interactions play a key role in cancer progression and response to standard
chemotherapy. Here, we provide a summary of the mechanisms by which the major cellular …

Ovarian cancer encompasses a heterogeneous group of malignancies that involve the
ovaries, fallopian tubes and the peritoneal cavity. Despite major advances made within the …

Ovarian adenocarcinoma is characterized by a late detection, dissemination of cancer cells
into the whole peritoneum, and the frequent acquisition of chemoresistance. If these …

In this study we aimed to analyze the biological mechanisms underlying apparently different
modes of peritoneal tumor spread in serous ovarian cancer: miliary (widespread, millet-like …

Ovarian cancer is the most lethal gynecologic malignancy and the fifth leading cause of
cancer-related death in women. Although outcomes have improved in recent years, there …

Despite chemotherapy and surgical debulking options, ovarian cancer recurs and
disseminates frequently, with poor prognosis. However, the molecular mechanisms …

Epithelial ovarian cancer is the fifth leading cause of cancer-related deaths in women and
the most lethal gynecological malignancy. Extracellular matrix (ECM) is an integral …

Unlike most epithelial malignancies which metastasize hematogenously, metastasis of
epithelial ovarian cancer (EOC) occurs primarily via transcoelomic dissemination …

Despite several advances in the understanding of ovarian cancer pathobiology, in terms of
driver genetic alterations in high-grade serous cancer, histologic heterogeneity of epithelial …