Serum levels of leptin, osteopontin, and sclerostin in patients with and without knee osteoarthritis

S Min, T Shi, X Han, D Chen, Z Xu, D Shi, H Teng… - Clinical …, 2021 - Springer
Objective To investigate the relationship between leptin, osteopontin (OPN), sclerostin
(SOST) and severity of knee osteoarthritis (KOA). Methods The study included 148 …

[HTML][HTML] Serum leptin and osteoporosis in postmenopausal women with primary knee osteoarthritis

WAA Elwakil, D Mohasseb, D Elkaffash… - The Egyptian …, 2016 - Elsevier
Aim of the work The purpose of this study was to evaluate the relationship of serum leptin
level and osteoporosis in postmenopausal women with knee osteoarthritis (KOA). Patients …

Serum leptin concentration positively correlates with body weight and total fat mass in postmenopausal Japanese women with osteoarthritis of the knee

J Iwamoto, T Takeda, Y Sato, H Matsumoto - Arthritis, 2011 - Wiley Online Library
The objective of the present study was to identify factors correlated with the serum leptin
concentration in women with knee OA. Fifty postmenopausal Japanese women with knee …

Correlation of synovial fluid leptin concentrations with the severity of osteoarthritis

JH Ku, CK Lee, BS Joo, BM An, SH Choi, TH Wang… - Clinical …, 2009 - Springer
Leptin is known to play an important role in the pathophysiology of osteoarthritis (OA). This
study investigated whether synovial fluid (SF) leptin level is related to the radiographic …

[HTML][HTML] Correlation between serum leptin, cytokines, cartilage degradation and functional impact in obese knee osteoarthritis patients

NA Hussein, G Sharara - The Egyptian Rheumatologist, 2016 - Elsevier
Aim of the work The aim of the present work was to correlate between serum level of leptin,
matrix metalloproteinase-13 (MMP13), interleukin-1β (IL1β), tumour necrosis factor (TNF-α) …

Elevated serum leptin may be associated with disease activity and secondary osteoporosis in Chinese patients with rheumatoid arthritis

X Gong, Y Tang, S Yu, W Shi, YR Wang, JL Deng… - Clinical …, 2023 - Springer
Introduction Rheumatoid arthritis (RA) is a systemic chronic autoimmune disease in adults
that is associated with significant joint issues and systemic inflammation. One of the signs of …

Circulating leptin and bone mineral density in rheumatoid arthritis

EA Aguilar-Chavez, JI Gamez-Nava… - The Journal of …, 2009 - jrheum.org
Objective. To evaluate the association between circulating leptin and bone mineral density
(BMD) in patients with rheumatoid arthritis (RA). Methods. One-hundred thirty …

Is serum leptin related to physical function and is it modifiable through weight loss and exercise in older adults with knee osteoarthritis?

GD Miller, BJ Nicklas, CC Davis… - International journal of …, 2004 - nature.com
OBJECTIVE: To determine the effect of weight loss and exercise interventions on serum
leptin and to investigate the relationship of physical function and osteoarthritis (OA) severity …

Significance of increased leptin expression in osteoarthritis patients

P Zhang, ZH Zhong, HT Yu, B Liu - PloS one, 2015 - journals.plos.org
Objective Alterations in leptin expression contributes to the progression of various diseases,
including cancers. This meta-analysis investigated the clinical significance of leptin levels in …

Serum leptin and resistin levels in knee osteoarthritis—Clinical and radiologic links: Towards precise definition of metabolic type knee osteoarthritis

SN Lambova, T Batsalova, D Moten, S Stoyanova… - Biomedicines, 2021 - mdpi.com
Obesity is considered a major risk factor for the development and progression of knee
osteoarthritis (OA). Apart from the mechanical effect of obesity via increase in mechanical …