Influence of cycle stage, age and endometrial biopsy score on oxytocin receptor distribution and gene expression in the cervix and uterus of non-pregnant mares

A Annandale, RM Stroehle, ML Schulman… - Theriogenology, 2018 - Elsevier
Persistent breeding-induced endometritis (PBIE) or delayed uterine clearance (DUC) are
major causes of mare subfertility. Oxytocin and its receptor are thought to play significant …

Endometrial prostaglandin synthases, ovarian steroids, and oxytocin receptors in mares with oxytocin-induced luteal maintenance

MR Rebordão, A Galvão, P Pinto-Bravo, J Pinheiro… - Theriogenology, 2017 - Elsevier
Oxytocin (OXT) has been used to prolong the luteal phase in mares, but its mechanism of
action is unknown. The aim of this study was to evaluate the effect of chronic exogenous …

Histomorphological endometrial status and influence of oxytocin on the uterine drainage and pregnancy rate in mares

K Rasch, HA Schoon, H Sieme… - Equine veterinary …, 1996 - Wiley Online Library
The aim of this field study was to examine the influence of the uterotonic substance oxytocin
in 2 different therapeutic dosages of 15 and 25 iu, respectively on the uterine drainage of …

Serum progesterone and oxytocinase, and endometrial and luteal gene expression in pregnant, nonpregnant, oxytocin, carbetocin and meclofenamic acid treated …

MD de Amorim, SA Bramer, GD Rajamanickam… - Theriogenology, 2023 - Elsevier
Our objectives were to examine changes in endometrial and luteal gene expression during
estrus, diestrus, pregnancy and treatments to induce luteolysis and putatively induce …

Expression of oxytocin receptors is greatly reduced in the placenta of heavy mares with retained fetal membranes due to secondary uterine atony

A Rapacz‐Leonard, A Raś, J Całka… - Equine veterinary …, 2015 - Wiley Online Library
Reasons for performing study Fetal membrane retention can be a life‐threatening condition
and its incidence exceeds 50% in heavy draught mares. Although fetal membrane retention …

Oxytocin receptor development in ovine uterus and cervix throughout pregnancy and at parturition as determined by in situ hybridization analysis

DC Wathes, HF Smith, ST Leung… - …, 1996 - rep.bioscientifica.com
The development of uterine oxytocin receptors is an important regulatory step in the initiation
of labour. Paracrine production of oxytocin by uterine and placental tissues may also be …

Coincident increases in oxytocin receptor expression and EMG responsiveness to oxytocin in the ovine cervix at oestrus

VJ Ayad, ST Leung, TJ Parkinson… - Animal Reproduction …, 2004 - Elsevier
This study has localised oxytocin receptor (OTR) mRNA expression within the cervix of non-
pregnant ewes and related this to changes in the sensitivity of the cervical musculature to …

A light microscopic and ultrastructural study on the presence and location of oxytocin in the equine endometrium

SE Bae, ED Watson - Theriogenology, 2003 - Elsevier
It has been reported that oxytocin is produced not only in the hypothalamus and posterior
pituitary but also in outside the classical hypothalamo–neurohypophyseal axis such as the …

Regulatory effect of steroid hormones and fetal tissues on expression of oxytocin receptor in the endometrium of late pregnant ewes

ST Leung, DC Wathes - Reproduction, 1999 - rep.bioscientifica.com
Oxytocin receptors play an important role in the establishment of pregnancy and parturition
in ruminants. Previous studies in cyclic and early pregnant ewes have indicated that …

Endometrial and luteal gene expression of putative gene regulators of the equine maternal recognition of pregnancy

MD de Amorim, SA Bramer, GD Rajamanickam… - Animal Reproduction …, 2022 - Elsevier
Our understanding of the temporal changes in endometrial and luteal gene transcripts
related to the actions of oxytocin and prostaglandin during early equine pregnancy is …