Toxicity assessment due to sub-chronic exposure to individual and mixtures of four toxic heavy metals

SJ Cobbina, Y Chen, Z Zhou, X Wu, T Zhao… - Journal of hazardous …, 2015 - Elsevier
Humans are exposed to a cocktail of heavy metal toxicants in the environment. Though
heavy metals are deleterious, there is a paucity of information on toxicity of low dose …

Low concentration toxic metal mixture interactions: Effects on essential and non-essential metals in brain, liver, and kidneys of mice on sub-chronic exposure

SJ Cobbina, Y Chen, Z Zhou, X Wu, W Feng, W Wang… - Chemosphere, 2015 - Elsevier
The deleterious effects of long term exposure to individual toxic metals in low doses are well
documented. There is however, a paucity of information on interaction of low dose toxic …

[HTML][HTML] Toxic effect of acute cadmium and lead exposure in rat blood, liver, and kidney

M Andjelkovic, A Buha Djordjevic, E Antonijevic… - International journal of …, 2019 - mdpi.com
Background: Cadmium and lead are widespread and non-biodegradable pollutants of great
concern to human health. In real life scenarios, we are exposed to mixtures of chemicals …

Oxidative stress induced by lead, cadmium and arsenic mixtures: 30-day, 90-day, and 180-day drinking water studies in rats: an overview

BA Fowler, MH Whittaker, M Lipsky, G Wang, XQ Chen - Biometals, 2004 - Springer
Humans are frequently exposed to combinations of lead (Pb), cadmium (Cd) and Arsenic
(As) but there is a paucity of actual data on the molecular effects of these agents at low dose …

Roles of biomarkers in evaluating interactions among mixtures of lead, cadmium and arsenic

G Wang, BA Fowler - Toxicology and applied pharmacology, 2008 - Elsevier
Human exposure to environmental chemicals is most correctly characterized as exposure to
mixtures of these agents. The metals/metalloids, lead (Pb), cadmium (Cd), and arsenic (As) …

Toxicity, mechanism and health effects of some heavy metals

M Jaishankar, T Tseten, N Anbalagan… - Interdisciplinary …, 2014 - sciendo.com
Heavy metal toxicity has proven to be a major threat and there are several health risks
associated with it. The toxic effects of these metals, even though they do not have any …

A review of toxicity and mechanisms of individual and mixtures of heavy metals in the environment

X Wu, SJ Cobbina, G Mao, H Xu, Z Zhang… - … Science and Pollution …, 2016 - Springer
The rational for the study was to review the literature on the toxicity and corresponding
mechanisms associated with lead (Pb), mercury (Hg), cadmium (Cd), and arsenic (As) …

Effects of subchronic exposure via drinking water to a mixture of eight water-contaminating metals: a biochemical and histopathological study in male rats

SH Jadhav, SN Sarkar, RD Patil, HC Tripathi - Archives of environmental …, 2007 - Springer
In the current study, we examined whether subchronic exposure via drinking water to low
doses of a mixture of metals (arsenic, cadmium, lead, mercury, chromium, manganese, iron …

Induction of oxidative stress in erythrocytes of male rats subchronically exposed to a mixture of eight metals found as groundwater contaminants in different parts of …

SH Jadhav, SN Sarkar, M Aggarwal… - Archives of environmental …, 2007 - Springer
Exposure of animals and humans to different metal components through contaminated
drinking water can result in a wide range of adverse clinical conditions. Toxicological …

[HTML][HTML] Assessment of individual and combined toxicities of four non-essential metals (As, Cd, Hg and Pb) in the microtox assay

AB Ishaque, L Johnson, T Gerald, D Boucaud… - International Journal of …, 2006 - mdpi.com
Although most researches with non-essential metals (NEMs) have been done with single or
individual metals, in reality, organisms are often exposed to multiple contaminants at the …