Several reports document the role of tumor necrosis factor alpha (TNF-α) and lipid
metabolism in the context of acute inflammation as a causative factor in obesity-associated …

Objectives Tumor necrosis factor-α (TNF-α) plays roles in the development of obesity, insulin
resistance, and possibility of Type 2 diabetes mellitus (T2DM). The objective of the current …

Chronic inflammation plays an important role in type 2 diabetes mellitus (T2DM), a common
endocrinological pro-inflammatory disorder associated with insulin resistance. The objective …

Tumor necrosis factor-α (TNF-α) is involved in insulin resistance and has long been a
candidate gene implicated in type 2 diabetes mellitus (T2DM), however the association …

Background & aim Tumor necrosis factor-α (TNF-α) and its genetic variants are implicated in
the development of type 2 diabetes (T2D) as a result of systemic inflammation, dyslipidemia …

Abstract Tumor Necrosis Factor-alpha (TNF-α) has been implicated in the pathogenesis of
insulin resistance and obesity. The increased expression of TNF-α in adipose tissue is …

Inflammation plays a crucial role in the pathogenesis of type 2 diabetes and various lines of
evidences suggest an important contribution of type 2 receptor for TNF α (TNFR2), a …

OBJECTIVES: We investigated two genetic markers in pro inflammatory molecules: TNFα-
308G/A and IL6-174G/C in order to assess their effect on type 2 diabetes (T2D) and obesity …

Background Type 2 diabetes mellitus is a metabolic condition associated with increased risk
of multiple organ complications. Genetic variations in TCF7L2, KCNJ11, CDKAL1, and FTO …

Methods: 50 type-2 diabetic patients attending Narayana Medical Hospital, Nellore, were
studied. Body mass index and Waist hip ratio were calculated. Homeostasis model …