Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions
Long noncoding RNAs (lncRNAs) are key regulators of chromatin state, yet the nature and
sites of RNA-chromatin interaction are mostly unknown. Here we introduce Chromatin …
sites of RNA-chromatin interaction are mostly unknown. Here we introduce Chromatin …
Chromatin isolation by RNA purification (ChIRP)
Long noncoding RNAs are key regulators of chromatin states for important biological
processes such as dosage compensation, imprinting, and developmental gene expression …
processes such as dosage compensation, imprinting, and developmental gene expression …
Understanding long noncoding RNA and chromatin interactions: what we know so far
K Mishra, C Kanduri - Non-coding RNA, 2019 - mdpi.com
With the evolution of technologies that deal with global detection of RNAs to probing of
lncRNA-chromatin interactions and lncRNA-chromatin structure regulation, we have been …
lncRNA-chromatin interactions and lncRNA-chromatin structure regulation, we have been …
Chromatin-associated RNA sequencing (ChAR-seq) maps genome-wide RNA-to-DNA contacts
RNA is a critical component of chromatin in eukaryotes, both as a product of transcription,
and as an essential constituent of ribonucleoprotein complexes that regulate both local and …
and as an essential constituent of ribonucleoprotein complexes that regulate both local and …
RADICL-seq identifies general and cell type–specific principles of genome-wide RNA-chromatin interactions
A Bonetti, F Agostini, AM Suzuki, K Hashimoto… - Nature …, 2020 - nature.com
Mammalian genomes encode tens of thousands of noncoding RNAs. Most noncoding
transcripts exhibit nuclear localization and several have been shown to play a role in the …
transcripts exhibit nuclear localization and several have been shown to play a role in the …
Characterization of the RNA content of chromatin
Noncoding RNA (ncRNA) constitutes a significant portion of the mammalian transcriptome.
Emerging evidence suggests that it regulates gene expression in cis or trans by modulating …
Emerging evidence suggests that it regulates gene expression in cis or trans by modulating …
Long noncoding RNAs: an emerging link between gene regulation and nuclear organization
S Quinodoz, M Guttman - Trends in cell biology, 2014 - cell.com
Mammalian genomes encode thousands of long noncoding RNAs (lncRNAs) that play
important roles in diverse biological processes. As a class, lncRNAs are generally enriched …
important roles in diverse biological processes. As a class, lncRNAs are generally enriched …
Long non-coding RNA and chromatin remodeling
P Han, CP Chang - RNA biology, 2015 - Taylor & Francis
Long noncoding RNAs (lncRNAs) are pivotal regulators of genome structure and gene
expression. LncRNAs can directly interact with chromatin-modifying enzymes and …
expression. LncRNAs can directly interact with chromatin-modifying enzymes and …
Nuclear fractionation reveals thousands of chromatin-tethered noncoding RNAs adjacent to active genes
MS Werner, AJ Ruthenburg - Cell reports, 2015 - cell.com
A number of long noncoding RNAs (lncRNAs) have been reported to regulate transcription
via recruitment of chromatin modifiers or bridging distal enhancer elements to gene …
via recruitment of chromatin modifiers or bridging distal enhancer elements to gene …
Long noncoding RNA as modular scaffold of histone modification complexes
Long intergenic noncoding RNAs (lincRNAs) regulate chromatin states and epigenetic
inheritance. Here, we show that the lincRNA HOTAIR serves as a scaffold for at least two …
inheritance. Here, we show that the lincRNA HOTAIR serves as a scaffold for at least two …