Anorexia nervosa (AN) is a debilitating and deadly disease characterized by low body mass
index due to diminished food intake, and oftentimes concurrent hyperactivity. A high …

Hypothalamic agouti-related peptide (AgRP) and neuropeptide Y-expressing neurons have
a critical role in driving food intake, but also in modulating complex, non-feeding behaviours …

Neurons expressing agouti-related protein (AgRP), the so-called hunger neurons, protect
mammals from starvation by promoting food-seeking behaviors (Trends Neurosci 36: 504 …

Feeding behavior is exquisitely regulated by homeostatic and hedonic neural substrates that
integrate energy demand as well as the reinforcing and rewarding aspects of food …

Sufficient feeding is essential for animals' survival, which requires a cognitive capability to
facilitate food seeking, but the neurobiological processes regulating food seeking are not …

Previous studies have shown that AgRP neurons in the arcuate nucleus (ARC) respond to
energy deficits and play a key role in the control of feeding behavior and metabolism. Here …

Dysregulation of body weight maintenance and opioid dependence are often treated as
independent disorders. Here, we assessed the effects of both acute and long-term …

The current obesity epidemic is a major worldwide health and economic burden. In the
modern environment, an increase in the intake of high-fat and high-sugar foods plays a …

Several different neuronal populations are involved in regulating energy homeostasis.
Among these, agouti-related protein (AgRP) neurons are thought to promote feeding and …

Maintaining energy homeostasis requires coordinating physiology and behavior both on an
acute timescale to adapt to rapid fluctuations in caloric intake and on a chronic timescale to …